Yu et al. observed that some trace elements in viscera of rats were changed by treatment of gossypol. In this note, the changes of some metal ions in rat bone and hair and feather of various animals treated with gossy...Yu et al. observed that some trace elements in viscera of rats were changed by treatment of gossypol. In this note, the changes of some metal ions in rat bone and hair and feather of various animals treated with gossypol were determined to observe the influence of gossypol on the metabolism of those elements. Pretreatment of bone, hair and feather and the method of determination were described in the previous paper.展开更多
Gossypol in a certain dose specifically destroys the spermatogenesis in some species of animals without any remarkable influence on the whole body. And lactate dehydrogenase-X (LDHX) is an isoenzyme peculiar to sperm ...Gossypol in a certain dose specifically destroys the spermatogenesis in some species of animals without any remarkable influence on the whole body. And lactate dehydrogenase-X (LDHX) is an isoenzyme peculiar to sperm and sperm-generating cells. In addition, gossypol is of the abolity to combine with protein (including enzyme). On these grounds, it is important to study the relation between LDH-X and gossypol.展开更多
Deoxycorticosterone acetate, injected daily for 5, 10, 20 or 30 days, reduced the serum potassium levels of rats by about 25%, a decrease that was independent of the treatment period employed. Serum sodium concentrati...Deoxycorticosterone acetate, injected daily for 5, 10, 20 or 30 days, reduced the serum potassium levels of rats by about 25%, a decrease that was independent of the treatment period employed. Serum sodium concentrations were unchanged with treatment duration. The potassium concentrations in extensor digitorum longus (EDL) and soleus (SOL) muscles were significantly decreased, and those of sodium increased, after treatment. Accompanying these changes of electrolyte concentration, the resting membrane potentials of treated EDL and SOL were hyperpolarized in vivo, and showed depolarization with the decreases of external potassium concentrations in vitro. The mitochondria in the muscles of treated rats were damaged. The degree of damage was more serious in EDL than in SOL and was dependent on the duration of deoxycorticosterone acetate treatment.展开更多
文摘Yu et al. observed that some trace elements in viscera of rats were changed by treatment of gossypol. In this note, the changes of some metal ions in rat bone and hair and feather of various animals treated with gossypol were determined to observe the influence of gossypol on the metabolism of those elements. Pretreatment of bone, hair and feather and the method of determination were described in the previous paper.
文摘Gossypol in a certain dose specifically destroys the spermatogenesis in some species of animals without any remarkable influence on the whole body. And lactate dehydrogenase-X (LDHX) is an isoenzyme peculiar to sperm and sperm-generating cells. In addition, gossypol is of the abolity to combine with protein (including enzyme). On these grounds, it is important to study the relation between LDH-X and gossypol.
文摘Deoxycorticosterone acetate, injected daily for 5, 10, 20 or 30 days, reduced the serum potassium levels of rats by about 25%, a decrease that was independent of the treatment period employed. Serum sodium concentrations were unchanged with treatment duration. The potassium concentrations in extensor digitorum longus (EDL) and soleus (SOL) muscles were significantly decreased, and those of sodium increased, after treatment. Accompanying these changes of electrolyte concentration, the resting membrane potentials of treated EDL and SOL were hyperpolarized in vivo, and showed depolarization with the decreases of external potassium concentrations in vitro. The mitochondria in the muscles of treated rats were damaged. The degree of damage was more serious in EDL than in SOL and was dependent on the duration of deoxycorticosterone acetate treatment.
