The continued application of electron microscopy as an adjunct procedure for the diagnosis of human diseases has been questioned in light of the explosive development and refinement of immunophenotyping, cytogenetic a...The continued application of electron microscopy as an adjunct procedure for the diagnosis of human diseases has been questioned in light of the explosive development and refinement of immunophenotyping, cytogenetic and molecular techniques (nucleic acid hybridization, molecular genetics, and the polymerase chain reaction). Accumulated fact demonstrated lately that a combination of immunohistochemistry and molecular techniques could not identify every disease and some diagnostic problems went unanswered. And immunohistochemistry sometimes produced results that are entirely convincing but incorrect. It is confirmed by our experience and that of many other investigations that electron microscopy can be applied to human disease diagnosis still as a powerful tool. It can help diagnose nonimmunoreactive diseases, nonneoplastic or neoplastic, clarify diagnoses in cases with complex and confusing immunophenotypes, promote understanding of the differentiation of new or controversial entities, and , as a result, enhance light microscopy diagnostic expertise.展开更多
This paper reports the stroke incidence rates in the People’s Republic of China(PRC)in 1986.A total of 5790864 people from 199 locations sampled from all parts of the PRC(Taiwanprovince excluded)were investigated and...This paper reports the stroke incidence rates in the People’s Republic of China(PRC)in 1986.A total of 5790864 people from 199 locations sampled from all parts of the PRC(Taiwanprovince excluded)were investigated and among them 6367 complete stroke cases were found.Theincidence rate was 109.95 per 100000 people and its 95% CI was 107.25～112.65/100000.The inci-dence rate adjusted using the population composition of the urban and rural areas of the PRCin 1986 was 110.58/100000.The incidence rate standardized by the direct method using thePRC population in 1982 was 84.07/100000,and the incidence rate standardized using theworld standard population was 115.87/100000.The incidence rates of the various provinces werecounted respectively,and the relationship between the incidence rates and the geographical locationswas analysed correlatively and regressively.Positive correlation and linear regression were found be-tween the incidence rotes and the latitudes and the longitudes,that is to say,the incidence rates in-creased gradually from the south to the north and decreased progressively from the east to the westin the PRC.The stroke incidence rates were higher in urban districts than in outskirts inbig cities.When the distribution of case number in months was analysed using the methods of thetest for trend and circular distribution,a peak significant in statistics was found in January althoughit was not very high.The stroke incidence rates rose gradualy with age,and the relationship be-tween the incidence rates and age could he fitted with the Logistic curve.展开更多
文摘The continued application of electron microscopy as an adjunct procedure for the diagnosis of human diseases has been questioned in light of the explosive development and refinement of immunophenotyping, cytogenetic and molecular techniques (nucleic acid hybridization, molecular genetics, and the polymerase chain reaction). Accumulated fact demonstrated lately that a combination of immunohistochemistry and molecular techniques could not identify every disease and some diagnostic problems went unanswered. And immunohistochemistry sometimes produced results that are entirely convincing but incorrect. It is confirmed by our experience and that of many other investigations that electron microscopy can be applied to human disease diagnosis still as a powerful tool. It can help diagnose nonimmunoreactive diseases, nonneoplastic or neoplastic, clarify diagnoses in cases with complex and confusing immunophenotypes, promote understanding of the differentiation of new or controversial entities, and , as a result, enhance light microscopy diagnostic expertise.
文摘This paper reports the stroke incidence rates in the People’s Republic of China(PRC)in 1986.A total of 5790864 people from 199 locations sampled from all parts of the PRC(Taiwanprovince excluded)were investigated and among them 6367 complete stroke cases were found.Theincidence rate was 109.95 per 100000 people and its 95% CI was 107.25～112.65/100000.The inci-dence rate adjusted using the population composition of the urban and rural areas of the PRCin 1986 was 110.58/100000.The incidence rate standardized by the direct method using thePRC population in 1982 was 84.07/100000,and the incidence rate standardized using theworld standard population was 115.87/100000.The incidence rates of the various provinces werecounted respectively,and the relationship between the incidence rates and the geographical locationswas analysed correlatively and regressively.Positive correlation and linear regression were found be-tween the incidence rotes and the latitudes and the longitudes,that is to say,the incidence rates in-creased gradually from the south to the north and decreased progressively from the east to the westin the PRC.The stroke incidence rates were higher in urban districts than in outskirts inbig cities.When the distribution of case number in months was analysed using the methods of thetest for trend and circular distribution,a peak significant in statistics was found in January althoughit was not very high.The stroke incidence rates rose gradualy with age,and the relationship be-tween the incidence rates and age could he fitted with the Logistic curve.
