Background Research has indicated that the triglyceride-glucose(Ty G)index is associated with the development and prognosis of cardiovascular diseases.However,there is still uncertainty regarding whether the Ty G inde...Background Research has indicated that the triglyceride-glucose(Ty G)index is associated with the development and prognosis of cardiovascular diseases.However,there is still uncertainty regarding whether the Ty G index can predict adverse cardiovascular events in patients with acute myocardial infarction(AMI).The present study aimed to explore the prognostic value of the Ty G index in patients with AMI.Methods AMI patients who underwent emergency percutaneous coronary intervention(PCI)in Guangdong General Hospital from February 2021 to June 2022 were enrolled.The study population was grouped based on the median Ty G index.The end point of the study was major adverse cardiovascular events(MACEs),defined as all-cause mortality,cardiogenic shock,recurrent myocardial infarction,acute attack of heart failure,repeat revascularization induced by cardiac ischemia,and urgent visit due to aggravation of chest pain.The Ty G index was calculated as follows:LN[fasting triglycerides(mg/d L)×fasting blood glucose(mg/d L)x1/2].Results A total of 196 patients were included.In the multivariate logistic regression analysis,Ty G index[odds ratio(OR):0.99,95%confidence interval(CI):0.45-2.16,P=0.98]was not significantly correlated with the occurrence of MACEs in AMI patients during hospitalization.Afterwards a total of 178 patients were followed up for an average of 12.66±5.35 months.In the multivariate Cox proportional hazards model,Ty G index[hazard ratio(HR):1.91,95%CI:1.02-3.6,P<0.05]were independent predictor of adverse events during follow-up,and the area under the receiver operating characteristic(ROC)curve(AUC)was0.63(0.53-0.73,P<0.05).Conclusions Ty G index can independently predict the prognosis of AMI patients during the follow-up period.[S Chin J Cardiol 2024;25(1):11-20]展开更多
基金supported by Medical Scientific Research Foundation of Guangdong Province(No.A2021025)National Natural Science Foundation of China(No.82000057)Science and Technology Project of Guangdong Province(No.2023A1515010177)。
文摘Background Research has indicated that the triglyceride-glucose(Ty G)index is associated with the development and prognosis of cardiovascular diseases.However,there is still uncertainty regarding whether the Ty G index can predict adverse cardiovascular events in patients with acute myocardial infarction(AMI).The present study aimed to explore the prognostic value of the Ty G index in patients with AMI.Methods AMI patients who underwent emergency percutaneous coronary intervention(PCI)in Guangdong General Hospital from February 2021 to June 2022 were enrolled.The study population was grouped based on the median Ty G index.The end point of the study was major adverse cardiovascular events(MACEs),defined as all-cause mortality,cardiogenic shock,recurrent myocardial infarction,acute attack of heart failure,repeat revascularization induced by cardiac ischemia,and urgent visit due to aggravation of chest pain.The Ty G index was calculated as follows:LN[fasting triglycerides(mg/d L)×fasting blood glucose(mg/d L)x1/2].Results A total of 196 patients were included.In the multivariate logistic regression analysis,Ty G index[odds ratio(OR):0.99,95%confidence interval(CI):0.45-2.16,P=0.98]was not significantly correlated with the occurrence of MACEs in AMI patients during hospitalization.Afterwards a total of 178 patients were followed up for an average of 12.66±5.35 months.In the multivariate Cox proportional hazards model,Ty G index[hazard ratio(HR):1.91,95%CI:1.02-3.6,P<0.05]were independent predictor of adverse events during follow-up,and the area under the receiver operating characteristic(ROC)curve(AUC)was0.63(0.53-0.73,P<0.05).Conclusions Ty G index can independently predict the prognosis of AMI patients during the follow-up period.[S Chin J Cardiol 2024;25(1):11-20]
