AIM:To explore the relationship between retinal exudative changes in neonates and perinatal toxoplasmosis,others,rubella,cytomegalovirus,and herpes simplex virus(TORCH)infections,as well as the characteristics of TORC...AIM:To explore the relationship between retinal exudative changes in neonates and perinatal toxoplasmosis,others,rubella,cytomegalovirus,and herpes simplex virus(TORCH)infections,as well as the characteristics of TORCH infection in neonates with retinal exudative changes.METHODS:Retrospective study.A total of 612 neonates with retinal exudative changes detected during ophthalmic screening in our hospital from May 2019 to March 2023 were selected.TORCH tests were performed on these neonates,and the results were subjected to statistical analysis to determine the infection characteristics.The neonates with retinal exudative changes were grouped by sex and age,the characteristics of TORCH infection were analyzed,and the positive rates were compared.RESULTS:Among the 612 neonates with retinal exudative changes,the highest positive rate was observed for cytomegalovirus(CMV-IgG)(96.7%),followed by rubella virus(RV-IgG)(73.9%).Mixed infections with two or three viruses were also observed,with the highest positive rate for mixed infection of RV-IgG and CMV-IgG reaching 71.2%.There was no statistically significant difference in TORCH infection among neonates of different sex(P>0.05).However,there were statistically significant differences in RV-IgG and CMV-IgM infections with retinal exudative changes among neonates of different age groups(P<0.05).CONCLUSION:Perinatal TORCH infection may be an important factor causing retinal exudative changes in neonates.The differences in various infections are not related to sex but are related to different age groups.展开更多
目的：探讨二十二碳六烯酸（DHA）联合物理综合疗法治疗弱视的效果。方法选择重庆市妇幼保健院眼科2011年至2012年3～5岁弱视患儿84例，按年龄、弱视性质、注视性质一致的原则随机分成3组。D H A组（口服DHA）；物理治疗组（进行遮盖加...目的：探讨二十二碳六烯酸（DHA）联合物理综合疗法治疗弱视的效果。方法选择重庆市妇幼保健院眼科2011年至2012年3～5岁弱视患儿84例，按年龄、弱视性质、注视性质一致的原则随机分成3组。D H A组（口服DHA）；物理治疗组（进行遮盖加精细作业组）；药物联合组（物理综合治疗同时联合DHA治疗）。治疗疗程均为6个月。每1～2个月进行门诊复查、随访，对视力结果进行治疗前后对比观察。结果 DHA组和药物联合组疗效优于物理治疗组（P＜0．05），且二者间的差异有随着弱视程度加重、年龄越小有逐渐增大的趋势。结论服用DHA可有效加强物理综合疗法对弱视的疗效。展开更多
目的分析重庆地区新生儿眼底疾病的发病情况及影响因素。方法对2016年1月至2019年11月在本院眼科使用Retcam3进行眼底病变筛查的38970例新生儿的筛查结果进行统计学分析。将新生儿分为足月儿和早产儿两组,分析两组眼底病变检出率。新生...目的分析重庆地区新生儿眼底疾病的发病情况及影响因素。方法对2016年1月至2019年11月在本院眼科使用Retcam3进行眼底病变筛查的38970例新生儿的筛查结果进行统计学分析。将新生儿分为足月儿和早产儿两组,分析两组眼底病变检出率。新生儿视网膜出血及渗出样改变的影响因素采用单因素分析及Logistic多因素回归分析。早产儿按胎龄和体质量分组,研究各组早产儿视网膜病变(retinopathy of prematurity,ROP)的检出率。结果足月儿组、早产儿组各病种总体异常检出率差异具有统计学意义(P=0.014)。受检足月儿34248例,共68496只眼,眼底异常检出率为24.97%;其中视网膜出血检出率最高(8131眼,11.871%),其次为视网膜渗出样改变(6611眼,9.652%)。经Logistic多因素回归分析,性别、胎龄、分娩方式对新生儿视网膜出血的发生有显著影响(P<0.001),性别、胎龄、分娩方式、母亲妊娠糖尿病对新生儿视网膜渗出样改变的发生有显著影响(P<0.001)。受检早产儿4722例,共9444只眼,ROP检出率为8.13%;不同体质量和胎龄的早产儿,ROP检出率有明显差异(P<0.05)。结论重庆地区新生儿视网膜出血、新生儿视网膜渗出等检出率较高,其中性别、胎龄、出生体质量、分娩方式、母亲妊娠糖尿病为引起新生儿眼底病变的高危因素。展开更多
文摘AIM:To explore the relationship between retinal exudative changes in neonates and perinatal toxoplasmosis,others,rubella,cytomegalovirus,and herpes simplex virus(TORCH)infections,as well as the characteristics of TORCH infection in neonates with retinal exudative changes.METHODS:Retrospective study.A total of 612 neonates with retinal exudative changes detected during ophthalmic screening in our hospital from May 2019 to March 2023 were selected.TORCH tests were performed on these neonates,and the results were subjected to statistical analysis to determine the infection characteristics.The neonates with retinal exudative changes were grouped by sex and age,the characteristics of TORCH infection were analyzed,and the positive rates were compared.RESULTS:Among the 612 neonates with retinal exudative changes,the highest positive rate was observed for cytomegalovirus(CMV-IgG)(96.7%),followed by rubella virus(RV-IgG)(73.9%).Mixed infections with two or three viruses were also observed,with the highest positive rate for mixed infection of RV-IgG and CMV-IgG reaching 71.2%.There was no statistically significant difference in TORCH infection among neonates of different sex(P>0.05).However,there were statistically significant differences in RV-IgG and CMV-IgM infections with retinal exudative changes among neonates of different age groups(P<0.05).CONCLUSION:Perinatal TORCH infection may be an important factor causing retinal exudative changes in neonates.The differences in various infections are not related to sex but are related to different age groups.
文摘目的：探讨二十二碳六烯酸（DHA）联合物理综合疗法治疗弱视的效果。方法选择重庆市妇幼保健院眼科2011年至2012年3～5岁弱视患儿84例，按年龄、弱视性质、注视性质一致的原则随机分成3组。D H A组（口服DHA）；物理治疗组（进行遮盖加精细作业组）；药物联合组（物理综合治疗同时联合DHA治疗）。治疗疗程均为6个月。每1～2个月进行门诊复查、随访，对视力结果进行治疗前后对比观察。结果 DHA组和药物联合组疗效优于物理治疗组（P＜0．05），且二者间的差异有随着弱视程度加重、年龄越小有逐渐增大的趋势。结论服用DHA可有效加强物理综合疗法对弱视的疗效。
文摘目的分析重庆地区新生儿眼底疾病的发病情况及影响因素。方法对2016年1月至2019年11月在本院眼科使用Retcam3进行眼底病变筛查的38970例新生儿的筛查结果进行统计学分析。将新生儿分为足月儿和早产儿两组,分析两组眼底病变检出率。新生儿视网膜出血及渗出样改变的影响因素采用单因素分析及Logistic多因素回归分析。早产儿按胎龄和体质量分组,研究各组早产儿视网膜病变(retinopathy of prematurity,ROP)的检出率。结果足月儿组、早产儿组各病种总体异常检出率差异具有统计学意义(P=0.014)。受检足月儿34248例,共68496只眼,眼底异常检出率为24.97%;其中视网膜出血检出率最高(8131眼,11.871%),其次为视网膜渗出样改变(6611眼,9.652%)。经Logistic多因素回归分析,性别、胎龄、分娩方式对新生儿视网膜出血的发生有显著影响(P<0.001),性别、胎龄、分娩方式、母亲妊娠糖尿病对新生儿视网膜渗出样改变的发生有显著影响(P<0.001)。受检早产儿4722例,共9444只眼,ROP检出率为8.13%;不同体质量和胎龄的早产儿,ROP检出率有明显差异(P<0.05)。结论重庆地区新生儿视网膜出血、新生儿视网膜渗出等检出率较高,其中性别、胎龄、出生体质量、分娩方式、母亲妊娠糖尿病为引起新生儿眼底病变的高危因素。
