探讨转氨酶(ALT)正常及轻度异常(<2ULN,upper limit of normal)的慢乙肝患者FibroScan与肝穿病理的关系。方法:选择我院2017年7月至2018年11月收治的ALT正常和轻度异常慢乙肝患者81例,均进行血液检查(包括乙肝六项、HBVDNA、肝功能等...探讨转氨酶(ALT)正常及轻度异常(<2ULN,upper limit of normal)的慢乙肝患者FibroScan与肝穿病理的关系。方法:选择我院2017年7月至2018年11月收治的ALT正常和轻度异常慢乙肝患者81例,均进行血液检查(包括乙肝六项、HBVDNA、肝功能等)、FibroScan、肝组织活检,根据肝脏病理分为观察组即有抗病毒治疗指征组(≥G2或≥S2)和对照组即无抗病毒治疗指征组(<G2或<S1),分析两组患者临床资料、肝组织炎症活动度评分(G)及肝纤维化程度分期(S)、肝脏的硬度值(LSM)。结果: 81例被纳入研究的患者中,大多数患者遭受不同程度的病理损伤,其中肝组织炎症为G2以上者43例(53.1%),肝纤维化程度分期为S2以上者23例(28.3%);观察组肝组织炎症活动度及肝纤维化程度(≥G2或≥S2)以及肝脏的硬度值(LSM)均高于对照组(<G2或<S1),差异有统计学意义(P<0.05)。结论:FibroScan在临床上指导转氨酶正常和轻度异常的慢性乙型肝炎患者抗病毒治疗及预后评估中,具有显著的应用价值。展开更多
We experimentally demonstrate a metamaterials（MMs）-based terahertz（THz） sensor to quickly distinguish the cancer tissues from normal tissues.The MMs-based THz sensor has two strong resonance absorption peaks at ab...We experimentally demonstrate a metamaterials（MMs）-based terahertz（THz） sensor to quickly distinguish the cancer tissues from normal tissues.The MMs-based THz sensor has two strong resonance absorption peaks at about 0.706 and 1.14 THz,respectively.When the sensor is covered with cancer tissues,the redshifts at about 0.706 and 1.14 THz are 31 and 19 GHz,respectively.However,if normal tissue is attached to the surface of the sensor,the corresponding redshifts are only 15 and 12 GHz,respectively.This study proposes a new method for quick diagnosis of early lung cancer and other cancers.展开更多
文摘探讨转氨酶(ALT)正常及轻度异常(<2ULN,upper limit of normal)的慢乙肝患者FibroScan与肝穿病理的关系。方法:选择我院2017年7月至2018年11月收治的ALT正常和轻度异常慢乙肝患者81例,均进行血液检查(包括乙肝六项、HBVDNA、肝功能等)、FibroScan、肝组织活检,根据肝脏病理分为观察组即有抗病毒治疗指征组(≥G2或≥S2)和对照组即无抗病毒治疗指征组(<G2或<S1),分析两组患者临床资料、肝组织炎症活动度评分(G)及肝纤维化程度分期(S)、肝脏的硬度值(LSM)。结果: 81例被纳入研究的患者中,大多数患者遭受不同程度的病理损伤,其中肝组织炎症为G2以上者43例(53.1%),肝纤维化程度分期为S2以上者23例(28.3%);观察组肝组织炎症活动度及肝纤维化程度(≥G2或≥S2)以及肝脏的硬度值(LSM)均高于对照组(<G2或<S1),差异有统计学意义(P<0.05)。结论:FibroScan在临床上指导转氨酶正常和轻度异常的慢性乙型肝炎患者抗病毒治疗及预后评估中,具有显著的应用价值。
基金supported by the National Natural Science Foundation of China(No.11574059)the Natural Science Foundation of Guangxi(Nos.2015GXNSFDA19039 and 2014GXNSFAA118376)the Foundation from Guangxi Key Laboratory of Automatic Detection Technology and Instrument(No.YQ14114)
文摘We experimentally demonstrate a metamaterials（MMs）-based terahertz（THz） sensor to quickly distinguish the cancer tissues from normal tissues.The MMs-based THz sensor has two strong resonance absorption peaks at about 0.706 and 1.14 THz,respectively.When the sensor is covered with cancer tissues,the redshifts at about 0.706 and 1.14 THz are 31 and 19 GHz,respectively.However,if normal tissue is attached to the surface of the sensor,the corresponding redshifts are only 15 and 12 GHz,respectively.This study proposes a new method for quick diagnosis of early lung cancer and other cancers.
