本研究以DPPH自由基清除能力为抗氧化活性衡量指标,利用双因素实验设计研究方法,探究了高压脉冲电场(PEF)的电场强度(5、10、15、20 k V/cm)和脉冲频率(1800、2400 Hz)两个因素对抗氧化肽MMCTN的抗氧化活性的影响,并且考察了PEF处理后...本研究以DPPH自由基清除能力为抗氧化活性衡量指标,利用双因素实验设计研究方法,探究了高压脉冲电场(PEF)的电场强度(5、10、15、20 k V/cm)和脉冲频率(1800、2400 Hz)两个因素对抗氧化肽MMCTN的抗氧化活性的影响,并且考察了PEF处理后保留时间(0、2 h)对其抗氧化活性的作用;借助傅立叶红外光谱技术(MIR)、圆二色谱技术(CD)分析了PEF处理对MMCTN的二级结构影响情况。研究发现,当电场强度为10 k V/cm,脉冲频率为2400 Hz,且PEF处理后保留2 h时,MMCTN的DPPH自由基清除能力最高,达到94.14%±0.13%;MIR光谱分析得知高压脉冲电场处理的样品功能团发生了改变;CD色谱分析得知PEF处理后的样品中α螺旋、β折叠、β转角和无规则卷曲之间发生了相互的转化。展开更多
目的:汉化重症监护口腔护理频率评估量表(Intensive Care Oral Care Frequency Assessment Scale,ICOCFAS)并检验其信度、效度。方法:在取得原作者的授权后,根据Brislin经典翻译模型对原量表进行直译、回译、跨文化调试和预调查,形成中...目的:汉化重症监护口腔护理频率评估量表(Intensive Care Oral Care Frequency Assessment Scale,ICOCFAS)并检验其信度、效度。方法:在取得原作者的授权后,根据Brislin经典翻译模型对原量表进行直译、回译、跨文化调试和预调查,形成中文版ICOCFAS量表,于2022年7月—9月采用便利抽样法选取南昌市某医院ICU的340例患者进行调查,评价该量表的信度和效度。结果:中文版ICOCFAS量表有1个维度,包含9个条目,累计方差贡献率为60.958%。条目水平的内容效度为0.889~1.000,平均量表水平效度为0.933。验证性因子分析结果显示,χ^(2)/df=2.887、RMSEA=0.074、RMR=0.016、GFI=0.932、CFI=0.955、NFI=0.933、TLI=0.940。量表的Cronbach’sα系数为0.920,重测信度为0.879。结论:中文版ICOCFAS量表具有良好的信度和效度,可作为ICU患者口腔护理频率的评估依据。展开更多
We present a magnetic scanning microscope equipped with a nitrogen-vacancy(NV) center scanning probe that has the ability to mechanically tune the strain of soft matter in-situ. The construction of the microscope and ...We present a magnetic scanning microscope equipped with a nitrogen-vacancy(NV) center scanning probe that has the ability to mechanically tune the strain of soft matter in-situ. The construction of the microscope and a continuous straintuning sample holder are discussed. An optically detected magnetic resonance protocol utilized in the imaging is described.In order to show the reliability of this microscope, the strain conduction is estimated with finite element simulation, and xray diffraction is required for calibration when freestanding crystal films are under consideration. A magnetic imaging result is displayed to demonstrate the nano-scale imaging capability. The microscope presented in this work is helpful in studying strain-coupled magnetic physics such as magnetic phase transition under strain and strain-tuned cycloidal orientation tilting.展开更多
文摘本研究以DPPH自由基清除能力为抗氧化活性衡量指标,利用双因素实验设计研究方法,探究了高压脉冲电场(PEF)的电场强度(5、10、15、20 k V/cm)和脉冲频率(1800、2400 Hz)两个因素对抗氧化肽MMCTN的抗氧化活性的影响,并且考察了PEF处理后保留时间(0、2 h)对其抗氧化活性的作用;借助傅立叶红外光谱技术(MIR)、圆二色谱技术(CD)分析了PEF处理对MMCTN的二级结构影响情况。研究发现,当电场强度为10 k V/cm,脉冲频率为2400 Hz,且PEF处理后保留2 h时,MMCTN的DPPH自由基清除能力最高,达到94.14%±0.13%;MIR光谱分析得知高压脉冲电场处理的样品功能团发生了改变;CD色谱分析得知PEF处理后的样品中α螺旋、β折叠、β转角和无规则卷曲之间发生了相互的转化。
文摘目的:汉化重症监护口腔护理频率评估量表(Intensive Care Oral Care Frequency Assessment Scale,ICOCFAS)并检验其信度、效度。方法:在取得原作者的授权后,根据Brislin经典翻译模型对原量表进行直译、回译、跨文化调试和预调查,形成中文版ICOCFAS量表,于2022年7月—9月采用便利抽样法选取南昌市某医院ICU的340例患者进行调查,评价该量表的信度和效度。结果:中文版ICOCFAS量表有1个维度,包含9个条目,累计方差贡献率为60.958%。条目水平的内容效度为0.889~1.000,平均量表水平效度为0.933。验证性因子分析结果显示,χ^(2)/df=2.887、RMSEA=0.074、RMR=0.016、GFI=0.932、CFI=0.955、NFI=0.933、TLI=0.940。量表的Cronbach’sα系数为0.920,重测信度为0.879。结论:中文版ICOCFAS量表具有良好的信度和效度,可作为ICU患者口腔护理频率的评估依据。
基金the National Natural Science Foundation of China (Grant Nos. 81788101, T2125011, 11861161004, and 12104447)the National Key R&D Program of China (Grant No. 2018YFA0306600)+5 种基金the Chinese Academy of Sciences (Grant Nos. XDC07000000, GJJSTD20200001,QYZDY-SSW-SLH004,Y201984, and YSBR-068)Innovation Program for Quantum Science and Technology (Grant Nos. 2021ZD0303204 and 2021ZD0302200)the Anhui Initiative in Quantum Information Technologies (Grant No. AHY050000)Hefei Comprehensive National Science CenterChina Postdoctoral Science Foundation (Grant No. 2020M671858)the Fundamental Research Funds for the Central Universities。
文摘We present a magnetic scanning microscope equipped with a nitrogen-vacancy(NV) center scanning probe that has the ability to mechanically tune the strain of soft matter in-situ. The construction of the microscope and a continuous straintuning sample holder are discussed. An optically detected magnetic resonance protocol utilized in the imaging is described.In order to show the reliability of this microscope, the strain conduction is estimated with finite element simulation, and xray diffraction is required for calibration when freestanding crystal films are under consideration. A magnetic imaging result is displayed to demonstrate the nano-scale imaging capability. The microscope presented in this work is helpful in studying strain-coupled magnetic physics such as magnetic phase transition under strain and strain-tuned cycloidal orientation tilting.
