Synthesis and photochemistry of acridin-9-ylmethoxycarbonyl （Amoc） as a new photochemically removable protecting group for alcohols were described. Three carbonates of alcohols 1-3 were synthesized through condensat...Synthesis and photochemistry of acridin-9-ylmethoxycarbonyl （Amoc） as a new photochemically removable protecting group for alcohols were described. Three carbonates of alcohols 1-3 were synthesized through condensation of 9-hydroxymethylacridine and chloroformates of alcohols, including benzyl alcohol, phenethyl alcohol and one galactose derivative. The photolysis of protected alcohols can efficiently release the corresponding alcohol in the efficiencies （Qulε） of 100-200 （quantum yield Qul=0.011-0.023, and molar absorptivity ε= 9.1 × 10^3-9.8 × 10^3 mol^-1·L·cm^-1） under 360 nm light.展开更多
基金Project supported by the National Natural Science Foundation of China （No. 30470444）.
文摘Synthesis and photochemistry of acridin-9-ylmethoxycarbonyl （Amoc） as a new photochemically removable protecting group for alcohols were described. Three carbonates of alcohols 1-3 were synthesized through condensation of 9-hydroxymethylacridine and chloroformates of alcohols, including benzyl alcohol, phenethyl alcohol and one galactose derivative. The photolysis of protected alcohols can efficiently release the corresponding alcohol in the efficiencies （Qulε） of 100-200 （quantum yield Qul=0.011-0.023, and molar absorptivity ε= 9.1 × 10^3-9.8 × 10^3 mol^-1·L·cm^-1） under 360 nm light.
