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氧化苦参碱对离体兔主动脉环的收缩作用 被引量:3
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作者 张虎生 李青 +1 位作者 侯华卫 王世久 《山西医科大学学报》 CAS 2006年第10期994-997,共4页
目的观察氧化苦参碱(oxymatrine,Om)对家兔离体胸主动脉环的收缩作用及其可能机制。方法按主动脉环实验方法,取兔胸主动脉制环,观察Om对累积量效曲线的影响。结果Om对家兔胸主动脉环具有剂量依赖性的收缩效应(10-4-10-1mol/L),酚妥拉明... 目的观察氧化苦参碱(oxymatrine,Om)对家兔离体胸主动脉环的收缩作用及其可能机制。方法按主动脉环实验方法,取兔胸主动脉制环,观察Om对累积量效曲线的影响。结果Om对家兔胸主动脉环具有剂量依赖性的收缩效应(10-4-10-1mol/L),酚妥拉明对此无拮抗作用;Om(10-4mol/L)使氯化钾累积量效曲线向左上方移动,维拉帕米(vera-pamil,Ver)可阻断此作用。Om可显著增强高浓度去甲肾上腺素(noradrenalin,NA)收缩血管的作用,Om(10-3mol/L)使氯化钙量效曲线向左上方移,最大效应增大,维拉帕米可阻断此作用。无钙液条件下Om对血管平滑肌不产生收缩作用。结论Om通过电压依赖性钙离子通道促进钙内流而收缩家兔离体胸主动脉环。 展开更多
关键词 氧化苦参碱 钙通道 主动脉
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Hydrothermal synthesis and characterization of Eu-doped GaOOH/α-Ga_2O_3/β-Ga_2O_3 nanoparticles 被引量:1
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作者 全玉 刘素琴 +3 位作者 黄可龙 方东 张学英 侯华卫 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2010年第8期1458-1462,共5页
Eu-doped GaOOH nanoparticles with size of 5-8 nm were prepared by hydrothermal method using sodium dodecylbenzene sulfonate (SDBS) as surfactant. Eu-doped α-Ga2O3 and β-Ga2O3 were further fabricated by annealing G... Eu-doped GaOOH nanoparticles with size of 5-8 nm were prepared by hydrothermal method using sodium dodecylbenzene sulfonate (SDBS) as surfactant. Eu-doped α-Ga2O3 and β-Ga2O3 were further fabricated by annealing GaOOH:Eu and then characterized by X-ray diffraction(XRD), transmission electron microscopy (TEM) and photoluminescence (PL). The TEM results show that monodisperse Eu^3+-doped GaOOH nanoparticles form and then transform into Eu^3+-doped a-Ga2O3 and β-Ga2O3 through annealing the GaOOH:Eu nanoparticles at 600 and 900℃, respectively. PL studies indicate that GaOOH:Eu has the highest intensity at 618 nm. Luminescence quenching is observed at higher Eu3+concentration in all samples. 展开更多
关键词 hydrothermal method GaOOH GA2O3 Eu-doped nanoparticle PHOTOLUMINESCENCE
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