细胞内热休克蛋白70积聚:人脑星形细胞瘤进展的标志之一

用ＨＳＰ７０单克隆抗体行免疫组化研究６１例不同恶性程度的人脑星形细脑瘤，发现３９例（６３９％）ＨＳＰ７０蛋白染色阳性，其中细胞核阳性３６例，细胞核和细胞浆阳性３例。３２例高恶度的星形细胞瘤中有２７例（８４３７％）阳性，其余２９例低恶度的肿瘤中有１２例（４１３７％）阳性，二者具有显性差异。高恶度的肿瘤中ＨＳＰ７０染色阳性细胞百分比亦高于低恶度的肿瘤。

急性创伤性颅内积气84例临床分析

急性创伤性颅内积气８４例临床分析广东省深圳市红十字会医院神经外科（５１８０２９）王建中，傅友增，陈耕野，陶唯宜０引言我院自１９９３年１月～１９９４年１２月共收治急性颅脑损伤病人７８０例，有急性创伤性颅内积气８４例，现报道如下：１临床资料本组８４例，男...

Clinical Research and Surgical Treatment of Posttraumatic Epilepsy

In order to investigate the susceptible factors of posttraumatic epilepsy (PTE) and the surgical treatment, the relative factors of 18 cases of intractable PTE and 35 cases of non-PTE patients with posttraumatic seizures (PTS) and the surgical treatment of PTE patients were studied retrospectively. The results showed that there was significant difference in the degree of unconsciousness after head injury, incidence of intracerebral hematoma and acute subdural hematoma between PTE group and non-PTE group. Of the 18 cases of PTE undergoing surgical treatment, the effectiveness of 11 cases was satisfactory and that of the remaining 7 was not. Between the two groups, there was difference in the localization of interictal epileptic discharge (IED) and ictal discharge (ID) as demonstrated by preoperative EEG. It was concluded that PTE was associated with the severity of head injury and intracranial hematoma. The localization of epileptogenic loci by preoperative EEG presumably contributed to the PTE surgical effects.

星形细胞瘤恶性进展过程中PCNA表达的研究

目的 研究增殖细胞核抗原 (PCNA)在星形细胞瘤中的表达与肿瘤病理分级的关系 ,讨论PCNA在星形细胞瘤预后判断上的价值。方法 SP免疫组化方法对 10 1例星形细胞瘤的PCNA表达进行观察 ,并着重对同一标本含有多个不同病理分级区的 2 2例肿瘤的PCNA阳性细胞百分率进行分析。结果 随着病理级别的升高 ,PCNA阳性细胞百分率升高。同一病例的不同病理分级区的PCNA的表达也呈同样的规律。结论 PCNA较准确地反映星形细胞瘤的增殖行为和恶性程度 。