目的探讨预先给予去甲肾上腺素对高龄患者腰硬联合麻醉髋关节置换术后认知功能的影响。方法方便选择该院2015年6月—2016年6月择期行髋关节手术的高龄患者60例,按随机数字表法将患者分为两组对照组(n=30)和去甲肾上腺素组(n=30)。用MMS...目的探讨预先给予去甲肾上腺素对高龄患者腰硬联合麻醉髋关节置换术后认知功能的影响。方法方便选择该院2015年6月—2016年6月择期行髋关节手术的高龄患者60例,按随机数字表法将患者分为两组对照组(n=30)和去甲肾上腺素组(n=30)。用MMSE量表进行认知功能评分,用ELISA法测定血浆S100-β蛋白浓度。结果去甲肾上腺素组术后1 d MMSE评分和血浆S100-β浓度分别为(25.4±1.70)分和(1.26±0.85)μg/L;对照组术后1 d MMSE评分和血浆S100-β浓度分别为(23.2±2.40)分和(4.08±1.05)μg/L,比较差异有统计学意义(P<0.05);去甲肾上腺素组术后1 d POCD发生率明显低于对照组,比较差异有统计学意义(P<0.05)。结论预先给予去甲肾上腺素能明显改善腰硬联合麻醉髋关节置换术患者术后认知功能障碍。展开更多
目的探讨乳腺癌根治术后患者自控镇痛(PCA)恶心呕吐的原因及各种止吐药的预防效果。方法选择140例在连续硬膜外麻醉下行乳腺癌根治术的女性患者,随机分为4组:A 组为对照组, 于手术切皮前静脉注射生理盐水4 ml;B 组于手术切皮前静脉注...目的探讨乳腺癌根治术后患者自控镇痛(PCA)恶心呕吐的原因及各种止吐药的预防效果。方法选择140例在连续硬膜外麻醉下行乳腺癌根治术的女性患者,随机分为4组:A 组为对照组, 于手术切皮前静脉注射生理盐水4 ml;B 组于手术切皮前静脉注射氟哌利多2.5 mg;C 组于手术切皮前静脉注射地塞米松10 mg;D 组于手术切皮前静脉注射恩丹西酮8 mg。术毕均行自控硬膜外芬太尼镇痛 (PCEFA)。观察术后24 h 内镇痛效果、镇痛评分和恶心呕吐发生情况。结果组间 VAS 评分、镇静评分、镇痛药量差异无显著性。A 组恶心发生率为51.4%,明显高于 B 组(31.4%,P<0.05),C 组和 D 组均为(14.3%,P<0.01);与 B 组比较,P<0.05;各处理组呕吐发生率显著低于 A 组(P<0.01),C 组和 D 组呕吐发生率又低于 B 组,(P<0.05);各处理组恶心呕吐程度均小于 A 组(P<0.05);C 组和 D 组相比恶心呕吐发生情况差异无显著性。结论术前单次分别给予一定量的氟哌利多、地塞米松、恩丹西酮均能不同程度的减少乳腺癌根治 PCA 恶心呕吐的发生,减轻恶心呕吐的程度;而地塞米松、恩丹西酮的效果更好。展开更多
OBJECTIVE: To compare the clinical effect of brachial plexus block with "One Injection Two Points" guided under ultrasound and the conventional method guiding by ultrasound. METHODS: 70 patients were randomi...OBJECTIVE: To compare the clinical effect of brachial plexus block with "One Injection Two Points" guided under ultrasound and the conventional method guiding by ultrasound. METHODS: 70 patients were randomized evenly into 2 groups, with 35 patients in each group, while the Experiment Group(Group B) received One Injection Two Points" method, the Control Group(Group A) received the conventional method.The nerve block every 5 s, the success rate of anesthesia, the dosage of local anesthetics, second remedial anesthesia, adverse reactions, etc.were recorded. RESULTS: Group B was superior to group A in the success rate of anesthesia; There were 6 patients in group A who required constant pump injection of Remifentanil to remedy, while no patients in Group B needed remedy treatment. There were no serious adverse reactions in both groups.CONCLUSIONS: The clinical effect of brachial plexus block with "One Injection Two Points" method guided under ultrasoundguiding by ultrasound was superior to that of the conventional method.展开更多
文摘目的探讨预先给予去甲肾上腺素对高龄患者腰硬联合麻醉髋关节置换术后认知功能的影响。方法方便选择该院2015年6月—2016年6月择期行髋关节手术的高龄患者60例,按随机数字表法将患者分为两组对照组(n=30)和去甲肾上腺素组(n=30)。用MMSE量表进行认知功能评分,用ELISA法测定血浆S100-β蛋白浓度。结果去甲肾上腺素组术后1 d MMSE评分和血浆S100-β浓度分别为(25.4±1.70)分和(1.26±0.85)μg/L;对照组术后1 d MMSE评分和血浆S100-β浓度分别为(23.2±2.40)分和(4.08±1.05)μg/L,比较差异有统计学意义(P<0.05);去甲肾上腺素组术后1 d POCD发生率明显低于对照组,比较差异有统计学意义(P<0.05)。结论预先给予去甲肾上腺素能明显改善腰硬联合麻醉髋关节置换术患者术后认知功能障碍。
文摘目的探讨乳腺癌根治术后患者自控镇痛(PCA)恶心呕吐的原因及各种止吐药的预防效果。方法选择140例在连续硬膜外麻醉下行乳腺癌根治术的女性患者,随机分为4组:A 组为对照组, 于手术切皮前静脉注射生理盐水4 ml;B 组于手术切皮前静脉注射氟哌利多2.5 mg;C 组于手术切皮前静脉注射地塞米松10 mg;D 组于手术切皮前静脉注射恩丹西酮8 mg。术毕均行自控硬膜外芬太尼镇痛 (PCEFA)。观察术后24 h 内镇痛效果、镇痛评分和恶心呕吐发生情况。结果组间 VAS 评分、镇静评分、镇痛药量差异无显著性。A 组恶心发生率为51.4%,明显高于 B 组(31.4%,P<0.05),C 组和 D 组均为(14.3%,P<0.01);与 B 组比较,P<0.05;各处理组呕吐发生率显著低于 A 组(P<0.01),C 组和 D 组呕吐发生率又低于 B 组,(P<0.05);各处理组恶心呕吐程度均小于 A 组(P<0.05);C 组和 D 组相比恶心呕吐发生情况差异无显著性。结论术前单次分别给予一定量的氟哌利多、地塞米松、恩丹西酮均能不同程度的减少乳腺癌根治 PCA 恶心呕吐的发生,减轻恶心呕吐的程度;而地塞米松、恩丹西酮的效果更好。
文摘OBJECTIVE: To compare the clinical effect of brachial plexus block with "One Injection Two Points" guided under ultrasound and the conventional method guiding by ultrasound. METHODS: 70 patients were randomized evenly into 2 groups, with 35 patients in each group, while the Experiment Group(Group B) received One Injection Two Points" method, the Control Group(Group A) received the conventional method.The nerve block every 5 s, the success rate of anesthesia, the dosage of local anesthetics, second remedial anesthesia, adverse reactions, etc.were recorded. RESULTS: Group B was superior to group A in the success rate of anesthesia; There were 6 patients in group A who required constant pump injection of Remifentanil to remedy, while no patients in Group B needed remedy treatment. There were no serious adverse reactions in both groups.CONCLUSIONS: The clinical effect of brachial plexus block with "One Injection Two Points" method guided under ultrasoundguiding by ultrasound was superior to that of the conventional method.