目的:分析25-羟基维生素D与DPN之间的关系。方法:选取2023年2月至2023年12月期间,在北华大学附属医院内分泌科住院的2型糖尿病患者99例,其中68例合并了周围神经病变(DPN),31例未合并周围神经病变(NDPN)。对两组之间的一般资料进行差异...目的:分析25-羟基维生素D与DPN之间的关系。方法:选取2023年2月至2023年12月期间,在北华大学附属医院内分泌科住院的2型糖尿病患者99例,其中68例合并了周围神经病变(DPN),31例未合并周围神经病变(NDPN)。对两组之间的一般资料进行差异性分析;logistic回归分析25-羟基维生素D与DPN之间的关系,并绘制受试者工作特征曲线(ROC)。结果:DPN组患者的年龄、糖尿病病程高于NDPN组患者(P P P P Objective: To analyze the relationship between 25-hydroxyvitamin D and DPN. Method: From February 2023 to December 2023, 99 patients with type 2 diabetes mellitus were hospitalized in the Department of Endocrinology, Affiliated Hospital of Beihua University, of which 68 had peripheral neuropathy (DPN) and 31 had no peripheral neuropathy (NDPN). Differences were analysed for general data between the two groups;logistic regression analysis was used to analyze the relationship between 25-hydroxyvitamin D and DPN, and the receiver operating characteristic curve (ROC) was plotted. Results: The age and duration of diabetes mellitus in the DPN group were higher than those in the NDPN group (P P P P < 0.05). Logistic regression multivariate analysis showed that the incidence of DPN increased by 19.1% for every 1 ng/ml decrease in 25-hydroxyvitamin D. The ROC curve area is 0.721. Conclusion: The level of 25-hydroxyvitamin D in patients with type 2 diabetes mellitus is significantly correlated with DPN. Evaluation of 25-hydroxyvitamin D may be a valuable part of the follow-up of patients with type 2 diabetes.展开更多
目的:探讨血尿酸/高密度脂蛋白胆固醇比值(UHR)与糖尿病性视网膜病变(DR)的相关性。方法:选择2023年3月~2024年3月于北华大学附属医院内分泌科住院的2型糖尿病患者共98例作为研究对象,收集临床资料及生化结果,计算BMI、UHR、甘油三酯/...目的:探讨血尿酸/高密度脂蛋白胆固醇比值(UHR)与糖尿病性视网膜病变(DR)的相关性。方法:选择2023年3月~2024年3月于北华大学附属医院内分泌科住院的2型糖尿病患者共98例作为研究对象,收集临床资料及生化结果,计算BMI、UHR、甘油三酯/高密度脂蛋白胆固醇比值(TG/HDL-C)等结果;对单纯2型糖尿病组(T2DM) 34例2型糖尿病性视网膜病变组(DR) 64例变量行差异性分析;logistic回归分析筛选DR高危因素并绘制受试者工作特征曲线(ROC曲线)。结果:与T2DM组比较,DR组病程、血尿酸(SUA)、UHR、甘油三酯(TG)、TG/HDL-C水平升高(p pp p p p Objective: to investigate the correlation between blood uric acid/high-density lipoprotein cholesterol ratio (UHR) and diabetic retinopathy (DR). Methods: A total of 98 patients with type 2 diabetes mellitus who were hospitalized in the Department of Endocrinology of Beihua University Hospital from March 2023 to March 2024 were selected as the study subjects. Clinical data and biochemical results were collected, and the results of BMI, UHR, and triglyceride/high-density lipoprotein cholesterol ratio (TG/HDL-C) were calculated;for the 34 cases of type 2 diabetes mellitus in the type 2 diabetes mellitus group (T2DM) alone and the 64 cases in the diabetic retinopathy group (DR), the differences in variables were analyzed. Retinopathy group (DR) 64 cases were analyzed;logistic regression analysis was performed to screen the risk factors of DR and to draw the working characteristic curve (ROC curve) of the subjects. Results: Compared with the T2DM group, the DR group had increased disease duration, blood uric acid (SUA), UHR, triglyceride (TG), and TG/HDL-C levels (p p p p p p < 0.05). Conclusion: UHR, SUA, TG, and TG/HDL-C are all risk factors for the development of DR, with UHR having the greatest predictive value for the development of DR.展开更多
文摘目的:分析25-羟基维生素D与DPN之间的关系。方法:选取2023年2月至2023年12月期间,在北华大学附属医院内分泌科住院的2型糖尿病患者99例,其中68例合并了周围神经病变(DPN),31例未合并周围神经病变(NDPN)。对两组之间的一般资料进行差异性分析;logistic回归分析25-羟基维生素D与DPN之间的关系,并绘制受试者工作特征曲线(ROC)。结果:DPN组患者的年龄、糖尿病病程高于NDPN组患者(P P P P Objective: To analyze the relationship between 25-hydroxyvitamin D and DPN. Method: From February 2023 to December 2023, 99 patients with type 2 diabetes mellitus were hospitalized in the Department of Endocrinology, Affiliated Hospital of Beihua University, of which 68 had peripheral neuropathy (DPN) and 31 had no peripheral neuropathy (NDPN). Differences were analysed for general data between the two groups;logistic regression analysis was used to analyze the relationship between 25-hydroxyvitamin D and DPN, and the receiver operating characteristic curve (ROC) was plotted. Results: The age and duration of diabetes mellitus in the DPN group were higher than those in the NDPN group (P P P P < 0.05). Logistic regression multivariate analysis showed that the incidence of DPN increased by 19.1% for every 1 ng/ml decrease in 25-hydroxyvitamin D. The ROC curve area is 0.721. Conclusion: The level of 25-hydroxyvitamin D in patients with type 2 diabetes mellitus is significantly correlated with DPN. Evaluation of 25-hydroxyvitamin D may be a valuable part of the follow-up of patients with type 2 diabetes.
文摘目的:探讨血尿酸/高密度脂蛋白胆固醇比值(UHR)与糖尿病性视网膜病变(DR)的相关性。方法:选择2023年3月~2024年3月于北华大学附属医院内分泌科住院的2型糖尿病患者共98例作为研究对象,收集临床资料及生化结果,计算BMI、UHR、甘油三酯/高密度脂蛋白胆固醇比值(TG/HDL-C)等结果;对单纯2型糖尿病组(T2DM) 34例2型糖尿病性视网膜病变组(DR) 64例变量行差异性分析;logistic回归分析筛选DR高危因素并绘制受试者工作特征曲线(ROC曲线)。结果:与T2DM组比较,DR组病程、血尿酸(SUA)、UHR、甘油三酯(TG)、TG/HDL-C水平升高(p pp p p p Objective: to investigate the correlation between blood uric acid/high-density lipoprotein cholesterol ratio (UHR) and diabetic retinopathy (DR). Methods: A total of 98 patients with type 2 diabetes mellitus who were hospitalized in the Department of Endocrinology of Beihua University Hospital from March 2023 to March 2024 were selected as the study subjects. Clinical data and biochemical results were collected, and the results of BMI, UHR, and triglyceride/high-density lipoprotein cholesterol ratio (TG/HDL-C) were calculated;for the 34 cases of type 2 diabetes mellitus in the type 2 diabetes mellitus group (T2DM) alone and the 64 cases in the diabetic retinopathy group (DR), the differences in variables were analyzed. Retinopathy group (DR) 64 cases were analyzed;logistic regression analysis was performed to screen the risk factors of DR and to draw the working characteristic curve (ROC curve) of the subjects. Results: Compared with the T2DM group, the DR group had increased disease duration, blood uric acid (SUA), UHR, triglyceride (TG), and TG/HDL-C levels (p p p p p p < 0.05). Conclusion: UHR, SUA, TG, and TG/HDL-C are all risk factors for the development of DR, with UHR having the greatest predictive value for the development of DR.
