Fifty-seven cases of nephrotic syndrome were treated with TCM decoctions as accessory treatment for prednisone and cyclophosphamide, and the effects were observed in a follow-up period of 5-15 years. The long-term com...Fifty-seven cases of nephrotic syndrome were treated with TCM decoctions as accessory treatment for prednisone and cyclophosphamide, and the effects were observed in a follow-up period of 5-15 years. The long-term complete remission rate of 68.4% and recurrence rate of 26.3% in the treatment group were respectively higher and lower than those in the control group (P<0.01, and P<0.01). The results suggested that the TCM decoctions were very helpful in treating this condition.展开更多
Objective: To observe the clinical effect of integrated traditional Chinese and western medicine (TCM-WM) in treating senile idiopathic nephrotic syndrome (SINS). Methods: Eighty-two patients of SINS were randomly div...Objective: To observe the clinical effect of integrated traditional Chinese and western medicine (TCM-WM) in treating senile idiopathic nephrotic syndrome (SINS). Methods: Eighty-two patients of SINS were randomly divided into two groups. The 41 patients in the TCM-WM group were treated with prednisone, Cytoxan (CTX) and Chinese medicinal herbs according to Syndrome-type, and the 41 patients in the control group were treated with western medicine alone. The clinical remission rate and time, recurrence rate in patients as well as adverse reaction rate occurred were observed. Results: The complete remission rate and total effective rate of the TCM-WM group were 58.5% and 85.4%, which were significantly higher than those of the control group (39.0% and 63.4%, P<0.01). The adverse reaction rate in the TCM-WM group was 36.6%, which was significantly lower than that of the control group (80.5%, P<0.01). A follow-up of 35.1±9.7 months showed that there was no significant difference in the recurrence rate between the two groups (P>0.05), but the average remission period (30.6±3.8 months) of the TCM-WM group was significantly longer than that of the control group (12.7±3.7 months, P<0.01). Conclusion: TCM-WM treatment is obviously superior to that with western medicine alone in increasing clinical remission rate, relieving adverse reaction rate and extending remission period.展开更多
文摘Fifty-seven cases of nephrotic syndrome were treated with TCM decoctions as accessory treatment for prednisone and cyclophosphamide, and the effects were observed in a follow-up period of 5-15 years. The long-term complete remission rate of 68.4% and recurrence rate of 26.3% in the treatment group were respectively higher and lower than those in the control group (P<0.01, and P<0.01). The results suggested that the TCM decoctions were very helpful in treating this condition.
文摘Objective: To observe the clinical effect of integrated traditional Chinese and western medicine (TCM-WM) in treating senile idiopathic nephrotic syndrome (SINS). Methods: Eighty-two patients of SINS were randomly divided into two groups. The 41 patients in the TCM-WM group were treated with prednisone, Cytoxan (CTX) and Chinese medicinal herbs according to Syndrome-type, and the 41 patients in the control group were treated with western medicine alone. The clinical remission rate and time, recurrence rate in patients as well as adverse reaction rate occurred were observed. Results: The complete remission rate and total effective rate of the TCM-WM group were 58.5% and 85.4%, which were significantly higher than those of the control group (39.0% and 63.4%, P<0.01). The adverse reaction rate in the TCM-WM group was 36.6%, which was significantly lower than that of the control group (80.5%, P<0.01). A follow-up of 35.1±9.7 months showed that there was no significant difference in the recurrence rate between the two groups (P>0.05), but the average remission period (30.6±3.8 months) of the TCM-WM group was significantly longer than that of the control group (12.7±3.7 months, P<0.01). Conclusion: TCM-WM treatment is obviously superior to that with western medicine alone in increasing clinical remission rate, relieving adverse reaction rate and extending remission period.
