目的探讨不同年龄段三阴性乳腺癌(triple negative breast cancer, TNBC)临床病理特征及预后影响因素。方法选取2018年1月~2021年1月医院收治的TNBC患者174例为研究对象,回顾性分析其临床资料,对比不同年龄段TNBC患者的临床病理特征,采...目的探讨不同年龄段三阴性乳腺癌(triple negative breast cancer, TNBC)临床病理特征及预后影响因素。方法选取2018年1月~2021年1月医院收治的TNBC患者174例为研究对象,回顾性分析其临床资料,对比不同年龄段TNBC患者的临床病理特征,采用单因素分析影响TNBC患者预后的相关因素,以Logistic回归分析明确危险因素。结果年轻组淋巴结转移、辅助化疗、Ki67高表达占比高于年老组(P<0.05);预后不良组Ⅲ期、>50岁、无根治性手术、辅助化疗、淋巴结转移、Ki67高表达占比高于预后良好组(P<0.05),预后不良组肿瘤直径大于预后良好组(P<0.05);Logistic回归分析显示肿瘤Ⅲ期、年龄>50、肿瘤直径、淋巴结转移均是影响TNBC患者预后的危险因素(P<0.05)。结论 TNBC患者的肿瘤Ⅲ期、年龄>50、肿瘤直径、淋巴结转移等病理特征是导致预后不良的危险因素。展开更多
In this paper, we reported the fuel cell performance with La0.8Sr0.2MnO3 （LSM）/Ce0.8Sm0.2O1.9 （SDC） composite cathode prepared from LSM powders of different particle sizes via the silk-printing technique. It was f...In this paper, we reported the fuel cell performance with La0.8Sr0.2MnO3 （LSM）/Ce0.8Sm0.2O1.9 （SDC） composite cathode prepared from LSM powders of different particle sizes via the silk-printing technique. It was found that the change in particle size ofLSM nanoparticle from 40 to 90 nm resulted in an increase in the maximum power density from 132 to 228 mW/cm2 at 650 ℃ with H2 as fuel and O2 as oxidant. And the polarization resistance of the electrode decreased from 2.547 to 1.034 Ω.cm2. Concerning the particle size of electrode materials, a higher activity was anticipated with smaller particles because a large number of TPB or electrode surface sites along with a higher porosity could be developed. However, this study showed that the electrode prepared with particles of larger diameter had fine and uniform microstructure resulting in higher power density and lower overpotential, where homogeneous distribution of particles and pores was beneficial for increasing the electrochemical active area and the electronic conductivity of the electrodes as well as the gas diffusion for the reactants.展开更多
基金Project supported by National Natural Science Foundation of China (21002012, 21173042)National Basic Research Program of China (973 Program) (2013CB932902)+1 种基金Educational Commission of Jiangsu Province (JHB 2011-2)Natural Science Foundation of Jiangsu Province (BK2011589)
文摘In this paper, we reported the fuel cell performance with La0.8Sr0.2MnO3 （LSM）/Ce0.8Sm0.2O1.9 （SDC） composite cathode prepared from LSM powders of different particle sizes via the silk-printing technique. It was found that the change in particle size ofLSM nanoparticle from 40 to 90 nm resulted in an increase in the maximum power density from 132 to 228 mW/cm2 at 650 ℃ with H2 as fuel and O2 as oxidant. And the polarization resistance of the electrode decreased from 2.547 to 1.034 Ω.cm2. Concerning the particle size of electrode materials, a higher activity was anticipated with smaller particles because a large number of TPB or electrode surface sites along with a higher porosity could be developed. However, this study showed that the electrode prepared with particles of larger diameter had fine and uniform microstructure resulting in higher power density and lower overpotential, where homogeneous distribution of particles and pores was beneficial for increasing the electrochemical active area and the electronic conductivity of the electrodes as well as the gas diffusion for the reactants.
