Ⅰ. INTRODUCTIONSodium Antimono Gallate (Code name Sb-273) is a sort of oral antimonial anti-Japanese schistosomiasis medicine. Through clinical appraisal, Sb-273 was officially accepted as of low toxicity, and since ...Ⅰ. INTRODUCTIONSodium Antimono Gallate (Code name Sb-273) is a sort of oral antimonial anti-Japanese schistosomiasis medicine. Through clinical appraisal, Sb-273 was officially accepted as of low toxicity, and since 1970, has been in production for general use for treatment of schistosomiasis. It is synthesized by the Institute of Medicine of Nanjing and is a powder of cream colour. By recrystallizing it in water solution, we obtained a colourless and transparent monocrystal bulk. Element composition form of展开更多
Kanglemeisu A (C50H63O19N·CH3OH) is the product of an actinomyces species from a soil sample gathered in China. Kanglemeisu A belongs to the triclinic system, space group P1,unit cell:a=12.760（3）, b=10.287（2）...Kanglemeisu A (C50H63O19N·CH3OH) is the product of an actinomyces species from a soil sample gathered in China. Kanglemeisu A belongs to the triclinic system, space group P1,unit cell:a=12.760（3）, b=10.287（2）, c=9.926（2） , α=88.39（2）,β=78.64（2）, γ=89.14（2）. RANTAN direct method is used to solve the structure.The final discrepancy factor is R=0.0689, after atom coordinates and temperature factors have been refined with full matrix least squares.The structure skeleton consists of four parts, the naphthalene nucleus connected to the 5-membered ring, a 17-membered ring connected to C2, a dimethyl butane diacid extended out from C20, β-D-3,4-OO’ methylenedigitoxose passing through an oxygen bridge O6 and linked to C27 of ansa ring.展开更多
文摘Ⅰ. INTRODUCTIONSodium Antimono Gallate (Code name Sb-273) is a sort of oral antimonial anti-Japanese schistosomiasis medicine. Through clinical appraisal, Sb-273 was officially accepted as of low toxicity, and since 1970, has been in production for general use for treatment of schistosomiasis. It is synthesized by the Institute of Medicine of Nanjing and is a powder of cream colour. By recrystallizing it in water solution, we obtained a colourless and transparent monocrystal bulk. Element composition form of
文摘Kanglemeisu A (C50H63O19N·CH3OH) is the product of an actinomyces species from a soil sample gathered in China. Kanglemeisu A belongs to the triclinic system, space group P1,unit cell:a=12.760（3）, b=10.287（2）, c=9.926（2） , α=88.39（2）,β=78.64（2）, γ=89.14（2）. RANTAN direct method is used to solve the structure.The final discrepancy factor is R=0.0689, after atom coordinates and temperature factors have been refined with full matrix least squares.The structure skeleton consists of four parts, the naphthalene nucleus connected to the 5-membered ring, a 17-membered ring connected to C2, a dimethyl butane diacid extended out from C20, β-D-3,4-OO’ methylenedigitoxose passing through an oxygen bridge O6 and linked to C27 of ansa ring.
