Present work was designed to quantitatively evaluate the performance of diffusion-weighted magnetic resonance imaging（DWI） in the diagnosis of the presence of metastasis in lymph nodes（LNs）. Eligible studies were ...Present work was designed to quantitatively evaluate the performance of diffusion-weighted magnetic resonance imaging（DWI） in the diagnosis of the presence of metastasis in lymph nodes（LNs）. Eligible studies were identified from systematical Pub Med and EMBASE searches. Data were extracted. Meta-analyses were performed to generate pooled sensitivity and specificity on the basis of per-node, per-lesion and per-patient, respectively. Fourteen publications（2458 LNs, 404 lesions and 334 patients） were eligible. Per-node basis demonstrated the pooled sensitivity and specificity was 0.82（P〈0.0001） and 0.90（P〈0.0001）, respectively. Per-lesion basis illustrated the pooled sensitivity and specificity was 0.73（P=0.0036） and 0.85（P〈0.0001）, respectively. Per-patient basis indicated the pooled sensitivity and specificity was 0.67（P=0.0909） and 0.86（P〈0.0001）, respectively. In conclusion, DWI has rather a negative predictive value for the diagnosis of LN metastasis presence. The difference of the mean apparent diffusion coefficients between benign and malignant LNs is not yet stable. Therefore, the DWI technique has to be further improved.展开更多
目的探讨低剂量MSCT摇篮扫描技术一站式全脑灌注与动态CTA检查的可行性及其在评价脑动脉瘤中的优越性。方法选择63例临床疑诊脑动脉瘤的患者,分为两组,动态CTA组(33例)应用80 k V和100 m As的MSCT摇篮扫描技术进行一站式全脑灌注与动态...目的探讨低剂量MSCT摇篮扫描技术一站式全脑灌注与动态CTA检查的可行性及其在评价脑动脉瘤中的优越性。方法选择63例临床疑诊脑动脉瘤的患者,分为两组,动态CTA组(33例)应用80 k V和100 m As的MSCT摇篮扫描技术进行一站式全脑灌注与动态CTA检查。常规CTA组(30例)CTA前平扫参数为100 k V和100 m As,CTA检查参数为100 k V和260 m As。对两组患者的辐射剂量与CTA图像质量分别进行比较;另对动态CTA组患者进行灌注分析。结果动态CTA组患者一站式脑灌注与动态CTA检查平均辐射剂量仅为(1.64±0.00)m Sv,常规CTA组患者平均辐射剂量为(1.68±0.17)m Sv,两组间差异无显著统计学意义(P>0.05)。动态CTA中最佳时相图像质量与常规CTA比较,血管强化程度及图像噪声较高,然而信噪比(SNR)、对比噪声比(CNR)差异无显著统计学意义(P>0.05)。94%(31/33)患者成功获得灌注图像,其中2例发现局限性灌注减低区域。结论低剂量MSCT摇篮扫描技术一站式脑灌注与CTA检查,能在不增加患者辐射剂量的前提下获得满意的图像质量,可实现脑动脉瘤患者动脉形态学与脑灌注功能的一站式综合评估。展开更多
文摘Present work was designed to quantitatively evaluate the performance of diffusion-weighted magnetic resonance imaging（DWI） in the diagnosis of the presence of metastasis in lymph nodes（LNs）. Eligible studies were identified from systematical Pub Med and EMBASE searches. Data were extracted. Meta-analyses were performed to generate pooled sensitivity and specificity on the basis of per-node, per-lesion and per-patient, respectively. Fourteen publications（2458 LNs, 404 lesions and 334 patients） were eligible. Per-node basis demonstrated the pooled sensitivity and specificity was 0.82（P〈0.0001） and 0.90（P〈0.0001）, respectively. Per-lesion basis illustrated the pooled sensitivity and specificity was 0.73（P=0.0036） and 0.85（P〈0.0001）, respectively. Per-patient basis indicated the pooled sensitivity and specificity was 0.67（P=0.0909） and 0.86（P〈0.0001）, respectively. In conclusion, DWI has rather a negative predictive value for the diagnosis of LN metastasis presence. The difference of the mean apparent diffusion coefficients between benign and malignant LNs is not yet stable. Therefore, the DWI technique has to be further improved.
文摘目的探讨低剂量MSCT摇篮扫描技术一站式全脑灌注与动态CTA检查的可行性及其在评价脑动脉瘤中的优越性。方法选择63例临床疑诊脑动脉瘤的患者,分为两组,动态CTA组(33例)应用80 k V和100 m As的MSCT摇篮扫描技术进行一站式全脑灌注与动态CTA检查。常规CTA组(30例)CTA前平扫参数为100 k V和100 m As,CTA检查参数为100 k V和260 m As。对两组患者的辐射剂量与CTA图像质量分别进行比较;另对动态CTA组患者进行灌注分析。结果动态CTA组患者一站式脑灌注与动态CTA检查平均辐射剂量仅为(1.64±0.00)m Sv,常规CTA组患者平均辐射剂量为(1.68±0.17)m Sv,两组间差异无显著统计学意义(P>0.05)。动态CTA中最佳时相图像质量与常规CTA比较,血管强化程度及图像噪声较高,然而信噪比(SNR)、对比噪声比(CNR)差异无显著统计学意义(P>0.05)。94%(31/33)患者成功获得灌注图像,其中2例发现局限性灌注减低区域。结论低剂量MSCT摇篮扫描技术一站式脑灌注与CTA检查,能在不增加患者辐射剂量的前提下获得满意的图像质量,可实现脑动脉瘤患者动脉形态学与脑灌注功能的一站式综合评估。
