Met-and Leu-eukephalin injected into lateral ventricles could decrease serumcorticosterone level in healthy rabbits.This effect could be reversed by giving naloxone.Fif-ty min after burn(third degree,30%) serum corti...Met-and Leu-eukephalin injected into lateral ventricles could decrease serumcorticosterone level in healthy rabbits.This effect could be reversed by giving naloxone.Fif-ty min after burn(third degree,30%) serum corticosterone of rabbits increased verysignificantly over controls,and pretreatment with dexamethazone had no negative feebdack ef-fect.Enkephalin failed to lower serum corticosterone from its increased level following burn.These results suggest that enkphalin act poasibly as a neurotransmitter or neuromodulatorwhich takes part in the modulation of corticosterone secretion.展开更多
文摘Met-and Leu-eukephalin injected into lateral ventricles could decrease serumcorticosterone level in healthy rabbits.This effect could be reversed by giving naloxone.Fif-ty min after burn(third degree,30%) serum corticosterone of rabbits increased verysignificantly over controls,and pretreatment with dexamethazone had no negative feebdack ef-fect.Enkephalin failed to lower serum corticosterone from its increased level following burn.These results suggest that enkphalin act poasibly as a neurotransmitter or neuromodulatorwhich takes part in the modulation of corticosterone secretion.