A novel chiral amino alcohol ligand, (1 R,2R,5S,7R,8R,9S ) 9 amino 8 hydroxycedrane was synthesized from cedranediol and reacted with borane to form the corresponding complex, oxazaborolidine, that was used as catalys...A novel chiral amino alcohol ligand, (1 R,2R,5S,7R,8R,9S ) 9 amino 8 hydroxycedrane was synthesized from cedranediol and reacted with borane to form the corresponding complex, oxazaborolidine, that was used as catalyst in the asymmetric reduction of prochiral ketones. Medium stereoselectivities were obtained.展开更多
文摘A novel chiral amino alcohol ligand, (1 R,2R,5S,7R,8R,9S ) 9 amino 8 hydroxycedrane was synthesized from cedranediol and reacted with borane to form the corresponding complex, oxazaborolidine, that was used as catalyst in the asymmetric reduction of prochiral ketones. Medium stereoselectivities were obtained.
