Optimization algorithm solving Lagrangian multipliers is the key of training SVM,determining the perfor-mance of SVM ,affecting practical applications of SVM in various fields widely. Some kinds of optimization algori...Optimization algorithm solving Lagrangian multipliers is the key of training SVM,determining the perfor-mance of SVM ,affecting practical applications of SVM in various fields widely. Some kinds of optimization algorithmsin SVM of overseas are introduced. We classify the optimization algorithms into two kinds: 1. the algorithms based onOsuna's decomposition strategy; 2. The iterative algorithms based on the changes of SVM formulation proposed byO. L. Mangasarian. We also analyze the characteristics of various optimization algorithms in SVM ,and predicting thetrend of research on optimization algorithm in SVM.展开更多
目的:探讨邻苯二甲酸二乙基己酯(DEHP)对新生小鼠睾丸及Leydig细胞形态结构及功能的影响。方法:DEHP分别以低、中、高3组剂量[100、200、500mg/(kg·d)]灌胃作用于怀孕12d到产后3d(GD12~PND3)的KM母鼠,观察DEHP对新生雄...目的:探讨邻苯二甲酸二乙基己酯(DEHP)对新生小鼠睾丸及Leydig细胞形态结构及功能的影响。方法:DEHP分别以低、中、高3组剂量[100、200、500mg/(kg·d)]灌胃作用于怀孕12d到产后3d(GD12~PND3)的KM母鼠,观察DEHP对新生雄性仔鼠体重、睾丸重量、Leydig细胞形态结构和3β-羟基类固醇脱氢酶(3β—HSD)活性、酶反应面积的影响。结果:DEHP作用于母鼠后,其雄性子代幼鼠体重和睾丸重量减轻,睾丸Leydig细胞形态、超微结构发生改变;高剂量组Leydig细胞数量明显增多;低、中剂量组睾酮合成关键酶3β-HSD酶活性下降,酶反应面积减小,但高剂量组在仔鼠出生后15d时酶活性降低[(吸光度值(0.154±0.011)1)8空白对照组(0.222±0.013),P〈0.01],而酶反应面积增大[(6303.0±745.6)μm^2 vs 空白对照组(5091.4±214.4)μm^2,P〈0.01)]。结论:DEHP能影响新生雄性小鼠体重、睾丸重量、Leydig细胞的形态结构和3B—HSD活性,具有抗雄激素效应。展开更多
文摘Optimization algorithm solving Lagrangian multipliers is the key of training SVM,determining the perfor-mance of SVM ,affecting practical applications of SVM in various fields widely. Some kinds of optimization algorithmsin SVM of overseas are introduced. We classify the optimization algorithms into two kinds: 1. the algorithms based onOsuna's decomposition strategy; 2. The iterative algorithms based on the changes of SVM formulation proposed byO. L. Mangasarian. We also analyze the characteristics of various optimization algorithms in SVM ,and predicting thetrend of research on optimization algorithm in SVM.
文摘目的:探讨邻苯二甲酸二乙基己酯(DEHP)对新生小鼠睾丸及Leydig细胞形态结构及功能的影响。方法:DEHP分别以低、中、高3组剂量[100、200、500mg/(kg·d)]灌胃作用于怀孕12d到产后3d(GD12~PND3)的KM母鼠,观察DEHP对新生雄性仔鼠体重、睾丸重量、Leydig细胞形态结构和3β-羟基类固醇脱氢酶(3β—HSD)活性、酶反应面积的影响。结果:DEHP作用于母鼠后,其雄性子代幼鼠体重和睾丸重量减轻,睾丸Leydig细胞形态、超微结构发生改变;高剂量组Leydig细胞数量明显增多;低、中剂量组睾酮合成关键酶3β-HSD酶活性下降,酶反应面积减小,但高剂量组在仔鼠出生后15d时酶活性降低[(吸光度值(0.154±0.011)1)8空白对照组(0.222±0.013),P〈0.01],而酶反应面积增大[(6303.0±745.6)μm^2 vs 空白对照组(5091.4±214.4)μm^2,P〈0.01)]。结论:DEHP能影响新生雄性小鼠体重、睾丸重量、Leydig细胞的形态结构和3B—HSD活性,具有抗雄激素效应。