耐酸型水性丙烯酸酯乳液的制备及性能

针对水性丙烯酸酯乳液耐酸性差的问题,以环氧树脂为改性剂,甲基丙烯酸甲酯为硬单体、丙烯酸丁酯/丙烯酸乙酯为功能单体,采用预乳化工艺和半连续种子乳液聚合法合成了一种新型乳液.利用红外光谱、热重分析仪、流变仪等分析了环氧树酯的改性效果,并采用正交实验优化了改性乳液、AES、PEG-400和OBSH对复合乳液涂料的固含量、润湿性和耐酸性能的影响.结果表明,当环氧树脂含量为2. 62%时,水性乳液的热稳定性较好,固含量达到44. 4%.复合乳液涂料最佳工艺配方为:水性丙烯酸酯乳液(150 g)、改性乳液(15 g)、AES(10 g)、PEG-400(1 g)、OBSH(0. 6 g).以环氧树脂改性乳液配制的复合乳液涂料漆膜亲水性得到明显改善,室温下可耐酸168 h,浸酸失重不高于1%.

Syntheses and Crystal Studies of Novel C-3’-N-sulfonyl and 7-O-acyl Modified Paclitaxel Analogues

Three C-3’-N-sulfonyl and C-7-O-acyl paclitaxel analogues were synthesized from 10-deacetyl baccatinⅢ(10-DAB)and their structures were confirmed by 1H NMR,13C NMR and HR-MS.Among them,the crystal structure of compound 9 b was determined by single-crystal X-ray diffraction.Compound 9 b crystallizes in monoclinic system,space group P21 with a=12.395(4),b=15.215(5),c=14.905(5)A,β=105.559(4)°and Z=2.In the structure,the introduction of the hydrophobic 3-fluorobenzoyl group at C(7)has little effect on the conformation of tetracyclic system.However,the conformation of the side-chain at C(13)in 9 b is quite different from that of paclitaxel and docetaxel.