目的:探讨白介素1受体相关激酶1在乳腺癌紫杉醇耐受患者治疗中的作用机制并作分析。方法:选取乳腺癌患者150例,其中包括Basal-like型乳腺癌、Luminal-A型乳腺癌、Luminal-B型乳腺癌、HER2过表达型乳腺癌及三阴乳腺癌各30例。获取所有参...目的:探讨白介素1受体相关激酶1在乳腺癌紫杉醇耐受患者治疗中的作用机制并作分析。方法:选取乳腺癌患者150例,其中包括Basal-like型乳腺癌、Luminal-A型乳腺癌、Luminal-B型乳腺癌、HER2过表达型乳腺癌及三阴乳腺癌各30例。获取所有参与对象的乳腺组织、乳腺癌组织,并应用实时荧光定量检测方法进行白介素1受体相关激酶1检测,并作比较分析。结果:五类型乳腺癌(Basal-like型、Luminal-A型、Luminal-B型、HER2过表达型、三阴)有紫杉醇耐受的IRAK1 m RNA相对表达水平均高于无紫杉醇耐受的IRAK1 m RNA相对表达水平,P<0.05。结论:在乳腺癌紫杉醇耐受患者治疗中白介素1受体相关激酶1有着重要作用意义及应用价值。展开更多
A process was proposed based on the combination of chemical and physical activation for the production of activated carbons used as the electrode material for electric double layer capacitor (EDLC). By material charac...A process was proposed based on the combination of chemical and physical activation for the production of activated carbons used as the electrode material for electric double layer capacitor (EDLC). By material characterization and electrochemical methods, the influences of the activitation process on the specific surface area, pore structure and electrochemical properties of the activated carbons were investigated. The results show that specific surface area, the mesopore volume, and the specific capacitance increase with the increase of the mass ratio of KOH to char (m(KOH)/m(char)) and the activation time, respectively. When m(KOH)/m(char) is 4.0, the specific surface area and the mesopore volume reach the maximum values, i.e. 1 960 m2/g and 0.308 4 cm3/g, and the specific capacitance is 120.7 F/g synchronously. Compared with the chemical activation, the activated carbons prepared by chemical-physical activation show a larger mesopore volume, a higher ratio of mesopore and a larger specific capacitance.展开更多
Polyaniline（PANI） nanofiber was synthesized by interfacial polymerization utilizing the interface between HC1 and CCl4. The hybrid type supercapacitors （PLi/C） based on Li-doping polyaniline and activated carbon e...Polyaniline（PANI） nanofiber was synthesized by interfacial polymerization utilizing the interface between HC1 and CCl4. The hybrid type supercapacitors （PLi/C） based on Li-doping polyaniline and activated carbon electrode were fabricated and compared with the redox type capacitors （PLi/PLi） based on two uniformly Li-doping polyaniline electrodes. The electrochemical performances of the two types of supercapacitors were characterized in non-aqueous electrolyte. PLi/C supercapacitors have a wider effective energy storage potential range and a higher upper potential. At the same time, the PLi/C supercapacitor exhibits a specific capacity of 120.93 F/g at initial discharge and retains 80% after 500 cycles. The ohmic internal resistance （REs） of PLi/C supercapacitor is 5.0 Ω, which is smaller than that of PLi/PLi capacitor （5.5 Ω）. Moreover, it can be seen that EtgNBF4 organic solution is more suitable for using as organic electrolyte of PLi/C capacitor compared with organic solution containing LiPFr.展开更多
H+ doped polyaniline nanofibre(PH) was synthesized by interfacial polymerization and polyanilines doped with Li salt(PLI and PHLI) were prepared by immersing emeraldine base(EB) and H+ doped polyaniline in 1 mol/L LiP...H+ doped polyaniline nanofibre(PH) was synthesized by interfacial polymerization and polyanilines doped with Li salt(PLI and PHLI) were prepared by immersing emeraldine base(EB) and H+ doped polyaniline in 1 mol/L LiPF6/(EC-EMC-DMC),respectively.PH,PLI and PHLI were all characterized by scanning electron microscopy(SEM) and Fourier transform infrared(FT-IR) spectrometry.With 1 mol/L LiPF6/(EC-EMC-DMC) as electrolyte,PH,PHLI and PLI were used as the active materials of symmetric non-aqueous redox supercapacitors.PLI shows the highest initial specific capacitance of 120 F/g(47 F/g for PH and 66 F/g for PHLI) among three samples.After 500 cycles,the specific capacitance of PLI remains 75 F/g,indicating the good cycleability.展开更多
文摘目的:探讨白介素1受体相关激酶1在乳腺癌紫杉醇耐受患者治疗中的作用机制并作分析。方法:选取乳腺癌患者150例,其中包括Basal-like型乳腺癌、Luminal-A型乳腺癌、Luminal-B型乳腺癌、HER2过表达型乳腺癌及三阴乳腺癌各30例。获取所有参与对象的乳腺组织、乳腺癌组织,并应用实时荧光定量检测方法进行白介素1受体相关激酶1检测,并作比较分析。结果:五类型乳腺癌(Basal-like型、Luminal-A型、Luminal-B型、HER2过表达型、三阴)有紫杉醇耐受的IRAK1 m RNA相对表达水平均高于无紫杉醇耐受的IRAK1 m RNA相对表达水平,P<0.05。结论:在乳腺癌紫杉醇耐受患者治疗中白介素1受体相关激酶1有着重要作用意义及应用价值。
基金Project(2007BAE12B01) supported by the National Key Technology Research and Development Program of China
文摘A process was proposed based on the combination of chemical and physical activation for the production of activated carbons used as the electrode material for electric double layer capacitor (EDLC). By material characterization and electrochemical methods, the influences of the activitation process on the specific surface area, pore structure and electrochemical properties of the activated carbons were investigated. The results show that specific surface area, the mesopore volume, and the specific capacitance increase with the increase of the mass ratio of KOH to char (m(KOH)/m(char)) and the activation time, respectively. When m(KOH)/m(char) is 4.0, the specific surface area and the mesopore volume reach the maximum values, i.e. 1 960 m2/g and 0.308 4 cm3/g, and the specific capacitance is 120.7 F/g synchronously. Compared with the chemical activation, the activated carbons prepared by chemical-physical activation show a larger mesopore volume, a higher ratio of mesopore and a larger specific capacitance.
基金Project(2008AA03Z207) supported by the National High-Tech Research and Development Program of China
文摘Polyaniline（PANI） nanofiber was synthesized by interfacial polymerization utilizing the interface between HC1 and CCl4. The hybrid type supercapacitors （PLi/C） based on Li-doping polyaniline and activated carbon electrode were fabricated and compared with the redox type capacitors （PLi/PLi） based on two uniformly Li-doping polyaniline electrodes. The electrochemical performances of the two types of supercapacitors were characterized in non-aqueous electrolyte. PLi/C supercapacitors have a wider effective energy storage potential range and a higher upper potential. At the same time, the PLi/C supercapacitor exhibits a specific capacity of 120.93 F/g at initial discharge and retains 80% after 500 cycles. The ohmic internal resistance （REs） of PLi/C supercapacitor is 5.0 Ω, which is smaller than that of PLi/PLi capacitor （5.5 Ω）. Moreover, it can be seen that EtgNBF4 organic solution is more suitable for using as organic electrolyte of PLi/C capacitor compared with organic solution containing LiPFr.
基金Project(2008AA03Z207) supported by the National Hi-tech Research and Development Program of China
文摘H+ doped polyaniline nanofibre(PH) was synthesized by interfacial polymerization and polyanilines doped with Li salt(PLI and PHLI) were prepared by immersing emeraldine base(EB) and H+ doped polyaniline in 1 mol/L LiPF6/(EC-EMC-DMC),respectively.PH,PLI and PHLI were all characterized by scanning electron microscopy(SEM) and Fourier transform infrared(FT-IR) spectrometry.With 1 mol/L LiPF6/(EC-EMC-DMC) as electrolyte,PH,PHLI and PLI were used as the active materials of symmetric non-aqueous redox supercapacitors.PLI shows the highest initial specific capacitance of 120 F/g(47 F/g for PH and 66 F/g for PHLI) among three samples.After 500 cycles,the specific capacitance of PLI remains 75 F/g,indicating the good cycleability.
