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替罗非班冠状动脉用药对急性ST段抬高型心肌梗死介入治疗患者的影响 被引量:4
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作者 库尔班尼沙·买买提 努尔比亚·玉苏甫 +1 位作者 艾比不拉·麦麦提 库尔班江·努尔 《心肺血管病杂志》 CAS 2023年第9期887-892,共6页
目的:观察替罗非班冠状动脉用药对急性ST段抬高型心肌梗死(ST-segment elevation myocardial infarction,STEMI)行经皮冠状动脉介入术(percutaneous coronary intervention,PCI)治疗患者的影响。方法:回顾性分析2018年3月至2021年3月,... 目的:观察替罗非班冠状动脉用药对急性ST段抬高型心肌梗死(ST-segment elevation myocardial infarction,STEMI)行经皮冠状动脉介入术(percutaneous coronary intervention,PCI)治疗患者的影响。方法:回顾性分析2018年3月至2021年3月,喀什地区第一人民医院收治的PCI联合替罗非班治疗的STEMI患者共96例,根据替罗非班用药方式将48例冠状动脉用药纳入观察组,将其中48例静脉注射纳入对照组。比较两组术前、术后3个月心功能指标、术前、术后即刻、术后24h、术后3个月心肌血流灌注指标(校正TIMI帧数)。记录术后1年两组患者心血管不良事件(major adverse cardiovascular events,MACE)发生情况。结果:术后3个月,两组LVEF高于术前,LVEDD、LVESD低于术前,观察组LVEF高于对照组,LVEDD、LVESD低于对照组,差异有统计学意义(P <0.05)。校正TIMI帧数组间、时点、组间*时点交互比较差异有统计学意义(P <0.05);两组术后即刻、术后24h、术后3个月校正TIMI帧数均低于术前(P <0.05),且术后即刻、术后24h、术后3个月观察组的校正TIMI帧数均低于对照组(P <0.05)。术后3个月,两组TIMI血流分为为2级、3级患者例数占比高于术前,观察组2级、3级患者例数占比高于对照组,差异有统计学意义(P <0.05);随访期间,两组MACE发生率比较,差异无统计学意义(P> 0.05)。结论:替罗非班冠状动脉用药可有效改善STEMI PCI患者心功能,促进心肌血流恢复,提升心肌灌注,且不会明显增加MACE风险。 展开更多
关键词 急性ST段抬高型心肌梗死 经皮冠状动脉介入术 替罗非班 心肌血流灌注 心血管不良事件
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Optimization of percutaneous coronary intervention through lower frame rates angiogram
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作者 艾比不拉·麦麦提 库尔班尼沙·买买提 +6 位作者 祖力米热·阿布力孜 奴热姑·阿布都卡得 布热比艳·太来提 阿布来提·阿不都热合曼 木拉提·阿比来列提 库尔班江·努尔 库提比丁·努尔 《South China Journal of Cardiology》 CAS 2023年第2期74-78,共5页
Background Coronary artery disease(CAD)is a leading cause of mortality worldwide.Percutaneous coronary intervention(PCI)is a standard treatment for CAD,yet the radiation exposure associated with this procedure can pos... Background Coronary artery disease(CAD)is a leading cause of mortality worldwide.Percutaneous coronary intervention(PCI)is a standard treatment for CAD,yet the radiation exposure associated with this procedure can pose significant risks to both patients and healthcare professionals.With the aim to optimize this procedure,we studied the effects of different exposure rates on radiation dose,fluoroscopy time,and procedural complications.Methods A total of 441 consecutive patients who underwent coronary angiography and subsequent PCI treatment from January 2020 to December 2021 were included in this study.Baseon the fluoroscopy frame rates used during the procedure,patients were divided into two groups,which included a standard dose protocol(SDP)group that used15 frames per second(FPS)and a low dose protocol(LDP)group that used 7.5 FPS.Then the impact of different fluoroscopy frame rates on total air kerma(AK),procedure time,fluoroscopy times(FT),and procedural complications in patients undergoing PCI were evaluated.Results Our data indicated that LDP group had a significantly lower AK,indicative of a reduced radiation dose,in comparison to SDP group.Although the procedure time and FT were slightly longer in the LDP group,this increase was not statistically significant.Moreover,the rate of intraoperative complications in the LDP group was not higher than that in the SDP group.In a subgroup of patients who underwent intravascular ultrasound(IVUS)within the LDP group,we observed further reductions in radiation exposure and FT.Conclusions The use of reduced fluoroscopy frame rates and adjunctive IVUS during PCI procedures can be a viable approach to minimizing radiation exposure without compromising procedure success or patient safety. 展开更多
关键词 Percutaneous coronary intervention Fluoroscopy frame rate Ionizing radiation Intravascular ultra-sound
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