黄连素具有广泛的生物学活性,包括但不限于抗炎、抗感染、调节肠道微生态以及抗肿瘤生长等效应。本文就黄连素在肠易激综合征、炎症性肠病及结直肠癌等肠道疾病治疗中的研究进展进行综述,以期为其临床应用提供参考。Berberine has multi...黄连素具有广泛的生物学活性,包括但不限于抗炎、抗感染、调节肠道微生态以及抗肿瘤生长等效应。本文就黄连素在肠易激综合征、炎症性肠病及结直肠癌等肠道疾病治疗中的研究进展进行综述,以期为其临床应用提供参考。Berberine has multiple biological activities, such as anti-inflammation, anti-infection, regulating intestinal microbiota and anti-tumour effects. This review summarizes the research progress of berberine in the treatment of irritable bowel syndrome, inflammatory bowel disease and colorectal cancer. It provides theoretical foundation for clinical practice of berberine in those intestinal diseases.展开更多
近些年,早发性结直肠癌(early-onset colorectal cancer, EOCRC)的发病率逐年上升。虽然目前其发病机制尚未完全明确,但与其相关潜在的危险因素,例如生活方式、饮食习惯、遗传易感性及肠道菌群的影响等逐渐被各项研究报道。本文通过回...近些年,早发性结直肠癌(early-onset colorectal cancer, EOCRC)的发病率逐年上升。虽然目前其发病机制尚未完全明确,但与其相关潜在的危险因素,例如生活方式、饮食习惯、遗传易感性及肠道菌群的影响等逐渐被各项研究报道。本文通过回顾国内外相关文献报道,对EOCRC的相关危险因素、预防做一综述,以提高人群对于EOCRC的预防意识,从而降低疾病的发生率。In recent years, the incidence rate of early-onset colorectal cancer (EOCRC) has increased year by year. Although its pathogenesis is not yet fully pinpointed, potential risk factors related to it, such as lifestyle, dietary habits, genetic susceptibility, and the influence of gut microbiota, have gradually been reported in various studies. This article reviews relevant literature reports at home and abroad to provide a review of the risk factors and prevention of EOCRC, in order to enhance the population’s awareness of EOCRC prevention, and thereby reduce the incidence of the disease.展开更多
文摘黄连素具有广泛的生物学活性,包括但不限于抗炎、抗感染、调节肠道微生态以及抗肿瘤生长等效应。本文就黄连素在肠易激综合征、炎症性肠病及结直肠癌等肠道疾病治疗中的研究进展进行综述,以期为其临床应用提供参考。Berberine has multiple biological activities, such as anti-inflammation, anti-infection, regulating intestinal microbiota and anti-tumour effects. This review summarizes the research progress of berberine in the treatment of irritable bowel syndrome, inflammatory bowel disease and colorectal cancer. It provides theoretical foundation for clinical practice of berberine in those intestinal diseases.
文摘近些年,早发性结直肠癌(early-onset colorectal cancer, EOCRC)的发病率逐年上升。虽然目前其发病机制尚未完全明确,但与其相关潜在的危险因素,例如生活方式、饮食习惯、遗传易感性及肠道菌群的影响等逐渐被各项研究报道。本文通过回顾国内外相关文献报道,对EOCRC的相关危险因素、预防做一综述,以提高人群对于EOCRC的预防意识,从而降低疾病的发生率。In recent years, the incidence rate of early-onset colorectal cancer (EOCRC) has increased year by year. Although its pathogenesis is not yet fully pinpointed, potential risk factors related to it, such as lifestyle, dietary habits, genetic susceptibility, and the influence of gut microbiota, have gradually been reported in various studies. This article reviews relevant literature reports at home and abroad to provide a review of the risk factors and prevention of EOCRC, in order to enhance the population’s awareness of EOCRC prevention, and thereby reduce the incidence of the disease.
