针刺蝶腭神经节治疗变应性鼻炎疗效的Meta分析

目的 系统评价针刺蝶腭神经节治疗变应性鼻炎的临床疗效。方法 计算机检索中国知网(China National Knowledge Internet,CNKI)、万方、维普(VIP China Science and Technology Journal Database,VIP)、中国生物医学(Chinese Bio Medical Literature Database,CBM)、PubMed、Web of Science、Cochrane Library数据库,针刺蝶腭神经节治疗变应性鼻炎的随机对照文献,剔除低质量文献,运用Rev Man5.4软件进行Meta分析。结果 9篇RCT共733例患者;Meta分析提示针刺蝶腭神经节可以改善患者生活质量(P=0.04,MD=5.62,95%CI=[0.24,10.99])、减轻变应性鼻炎四大主症(P=0.02,MD=1.24,95%CI=[0.23,2.25])、对变应性鼻炎的治疗总有效率优于常规治疗(P=0.002,RR=1.15,95%CI=[1.05,1.26]),尤其优于常规针刺。结论 针刺蝶腭神经节治疗变应性鼻炎简便易行,疗效确切,可显著改善患者症状,提高生活质量,建议临床推广应用。

Experimental and numerical investigation on the uniformity of nanosecond pulsed dielectric barrier discharge influenced by pulse parameters

Nanosecond(ns)pulsed dielectric barrier discharge(DBD)is considered as a promising method to produce controllable large-volume and high activity low-temperature plasma at atmospheric pressure,which makes it suitable for wide applications.In this work,the ns pulse power supply is used to excite Ar DBD and the influences of the pulse parameters(voltage amplitude,pulse width,pulse rise and fall times)on the DBD uniformity are investigated.The gas gap voltage(Ug)and conduct current(Ig)are separated from the measured voltage and current waveforms to analyze the influence of electrical parameters.The spectral line intensity ratio of two Ar excited species is used as an indicator of the electron temperature(Te).The time resolved discharge processes are recorded by an intensified charge-coupled device camera and a one-dimensional fluid model is employed to simulate the spatial and temporal distributions of electrons,ions,metastable argon atoms and Te.Combining the experimental and numerical results,the mechanism of the pulse parameters influencing on the discharge uniformity is discussed.It is shown that the space electric field intensity and the space particles'densities are mainly responsible for the variation of discharge uniformity.With the increase of voltage and pulse width,the electric field intensity and the density of space particles increased,which results in the discharge mode transition from non-uniform to uniform,and then non-uniform.Furthermore,the extension of pulse rise and fall times leads to the discharge transition from uniform to nonuniform.The results are helpful to reveal the mechanism of ns pulsed DBD mode transition and to realize controllable and uniform plasma sources at atmospheric pressure.