电刺激兔耳穴对胆囊收缩的影响

本实验发现电刺激兔耳肝胆穴后,胆囊缩小,胆囊颜色变淡,其缩小反应最早在刺激后1分钟时出现,多在刺激后10分钟左右收缩开始明显,一般持续30～40分钟。取刺激后15～25分钟所得的胆囊长径和宽径乘积的平均值,与刺激前比较,差异显著。这一结果不但由体外观察到有关耳穴与肝胆脏器的相关关系。也为临床上采用耳压排石疗法提供了理论基础。

兔肝胆汁中微量元素的含量及刺激兔耳“肝胆穴”对其含量的影响

用电感耦合等离子直读光谱仪测定正常家兔肝胆汁中微量元素含量,结果发现兔肝胆汁中含有23种元素,其中14种元素浓度高于检出下限,大多为金属元素,亦有少量非金属元素。这结果与黑色胆石成分基本一致。在刺激兔耳肝胆穴后,观察到肝胆汁中一些必需金属元素如铜、铁、镁等的含量都有所下降,尤以钠浓度下降明显。以上结果为进一步探讨耳压法预防结石症产生提供了依据。

藻蓝蛋白对小鼠粒单系祖细胞生成的影响

藻蓝蛋白(C—phycocyanin,C—PC)是从钝顶螺旋藻(Spirulina platensis)中分离、纯化所得。采用造血祖细胞体外培养技术,研究了C—PC对小鼠粒单系祖细胞生成的影响。实验结果表明,C—PC能够提高粒单系祖细胞(CFU—GM)的生成,亦能明显提高正常小鼠血清的集落刺激活性。C—PC体内或体外刺激制备的小鼠脾细胞条件培养液能明显增加CFU—GM的集落数。在有集落刺激因子(GM—CSF)存在时,体外加入C—PC培养粒单系祖细胞,C—PC能明显提高CFU—GM的集落生成率。

螺旋藻多糖对放烧复合伤所致小鼠造血功能抑制的保护作用

目的 观察螺旋藻多糖 (SPP)对放烧复合伤所致造血功能抑制的保护作用。方法 小鼠 5Gy全身照射复合 15 %Ⅲ度烧伤后 5、10、15d分别取材 ,作骨髓粒单系、红系造血祖细胞培养 ,造血干细胞集落测定 ,以及外周血常规计数等。SPP用量为 12 5mg·kg-1·d-1,ip ,伤后连续注射 6d。结果 放烧复合伤后骨髓有核细胞数、粒单系CFU GM、红系CFU E、BFU E及造血干细胞CFU S集落数均显著低于正常对照组 (P <0 0 1) ,但应用SPP后 ,上述各项指标数值 ,均比同伤情的不用药组显著提高 ,尤以伤后 10d恢复最快 (P <0 0 1)。

锰(Ⅱ)传感器的研制及应用

锰是一切生物体内不可缺少的微量元素,与很多生理现象有关。过量的锰却是一种有害物质,某些胆结石患者结石中含有一定量的锰,约占0.72％左右,它与胆结石的形成有着密切关系。目前用于测量胆结石中锰含量的传感器的报道较少。

电极刺激兔耳肝胆穴对迷走背核突触亚微结构的影响

耳针的应用早就受到重视,对多种疾病的临床观察已肯定了耳针的疗效。采用耳压法治疗胆石症也有显著的临床效果,近年来的病例日益增多。然而。

钝顶螺旋藻多糖和藻蓝蛋白对小鼠急性放射病的防护作用

本文报告了钝顶螺旋藻多糖（ＳＰＰ）和藻蓝蛋白（Ｃ－ＰＣ）对小鼠受致死剂量￣（６０）Ｃｏγ射线照射后３０天存活率的影响。在照射前５天每天给小鼠腹腔注射ＳＰＰ１２５ｍｇ／ｋｇ或Ｃ－ＰＣ５０ｍｇ／ｋｇ均能分别比对照组提高小鼠的存活率３３％和２８％同时观察了ＳＰＰ和Ｃ－ＰＣ对经￣（６０）Ｃｏγ射线亚致死剂量照射后小鼠血细胞生成的影响，结果显示，ＳＰＰ和Ｃ－ＰＣ可刺激照射后小鼠粒单系祖细胞和造血干细胞的形成，并增加骨髓有核细胞的数量。ＳＰＰ和Ｃ－ＰＣ还可以增加照射小鼠外周血细胞的总数。ＳＰＰ和Ｃ－ＰＣ对外周血红细胞数与血红蛋白量无显著的影响。结果提示：ＳＰＰ和Ｃ－ＰＣ可能促进￣（６０）Ｃｏγ射线照射小鼠造血功能的恢复。

寓思想教育于科学知识的传授中

4月8日,本刊编辑部邀请部分全国人大代表和全国政协委员座谈思想政治工作。他们就当前如何加强和改进青年思想教育工作谈了许多很好的意见。现将他们的发言刊登如下,以飨读者。

ANALGESIC EFFECTS OF LANTHANIDES, EGTA, MORPHINE AND ELECTRIC ACUPUNCTURE

Our previous and recent studies have found that lanthanides La3+ and Pr3+themselves not only have marked analgesic effect, but can also produce a synergistic effect in coordination with electric acupuncture analgesia. The analgesic effect can be antagonized by calcium and naloxone, and so its analgesic characteristic is very similar to those of morphine and electric acupuncture. There are 15 lanthanides, and their chemical and physical properties are very similar. It follows that

RELATIONSHIP OF BRAIN CALCIUM AND POTASSIUM CONTENTS TO ELECTRIC ACUPUNCTURE ANALGESIA

Relationship of calcium and magnesium contents in mouse brain to electric acupuncture analgesia has been well studied. Recently workers found that both analgesic effects of electric acupuncture and morphine not only were similar, but also had a common ionic basis. The subcellular loss of calcium after opiate administration was found to be associated with fractions rich in nerve endings and was closely parallel to the subcellular distribution of opiate receptor binding, and was shown to be influenced by a number of inorganic ions, particularly monovalent and divalent cations implicated

THE COMMON BASIS OF ELECTRO-ACUPUNCTURE ANALGESIA AND MORPHINE ANALGESIA

The correlation of 12 metal ions with electro-acupuncture analgesia in mice was studied. It was found that a decrease of calcium ion (Ca2+) content in the brain could enhance the analgesic effect of electro-acupuncture, while an increase of Ca2+ content could lower or even cancel its effect. Other cations, such as potassium, sodium, lithium, copper, strontium, barium, zinc, cobalt, ferrous, magnesium and aluminum, had no effect on electro-acupuncture analgesia.