基金sincerely appreciate the financial support from the National Natural Science Foundation of China(51673017 and 62004138)Beijing National Laboratory for Molecular Sciences(BNLMS202006)+2 种基金the Fundamental Research Funds for the Central Universities(XK1802-2)the National Key Basic Research Program of China(973 program,2014CB643604)the Natural Science Foundation for Distinguished Young Scholars of Jiangsu Province(BK20140006)。