以螺旋藻为主壁材的亚麻油微胶囊制备

以螺旋藻为主要壁材,以亚麻油为芯材,通过喷雾干燥技术制备微胶囊。考察了喷雾干燥工艺参数及进料配方对微胶囊产品质量的影响,筛选出明胶和麦芽糊精作为辅助壁材,并对微胶囊产品的性能进行了一系列表征。研究结果表明:单一螺旋藻壁材包埋亚麻油微胶囊的最佳制备条件为空气压力3 bar,空气流速4.3 m/s,进口温度190℃,进料流量900 m L/h,进料质量分数10%,芯壁材质量比1∶3,在此条件下微胶囊包埋率为48.85%。与单一螺旋藻壁材相比,复合壁材微胶囊具备更高的包埋率,以螺旋藻为主壁材,以明胶和麦芽糊精为辅助壁材制备的亚麻油微胶囊包埋率可提升至75.36%。通过表征分析及性能检测可知,喷雾干燥制备的螺旋藻微胶囊表面光滑,颗粒圆、尺寸小,平均粒径为7.20μm,且抗氧化性与市售螺旋藻粉相比提高47.7%。螺旋藻与明胶、麦芽糊精复配制得的微胶囊具有良好的热稳定性和储存稳定性,当温度由40℃升至200℃时,复合壁材微胶囊的质量保持率为82.96%;复合壁材微胶囊能有效延缓芯材亚麻油的氧化进程,且室温储存30 d后微胶囊芯材保留率仍维持在80%以上。

Alginate-Casein Microspheres as Bioactive Vehicles for Nutrients

The aim of this work was to develop an alginate-casein composite microsphere as a bioaetive vehicle for oral administration of nutrients by a simple extrusion dripping method. Riboflavin was selected as a model drug, and the microencapsulation efficiency was raised to 97.94% after optimizing the preparation conditions by response surface methodology. In vitro release studies showed that riboflavin was released completely from alginate-casein microspheres in simulated intestinal fluids. Meanwhile, the morphology, structure and interaction between alginate and casein were characterized by scanning electron microscopy （SEM） and Fourier transform infrared （FTIR） spectra.

影响石油化工管道设计的因素及解决措施

对于石油化工行业而言,管道是运输石油的主要方式。由于石油本身具有比较特殊的性质,致使其对管道的设计要求较多。为了确保石油可以得到安全性的运输,相关人员就必须严格按照规定标准对管道进行设计,便于石油进行运输。