围产期抑郁症(PND)是女性围产期内经历的精神障碍性疾病,严重威胁孕产妇及子代身心健康。PND的发生与女性生理、心理、经济和社会等多因素综合作用相关,发病机制尚不完全清楚。早期诊断和及早干预、治疗是防止抑郁加重,降低围产期女性...围产期抑郁症(PND)是女性围产期内经历的精神障碍性疾病,严重威胁孕产妇及子代身心健康。PND的发生与女性生理、心理、经济和社会等多因素综合作用相关,发病机制尚不完全清楚。早期诊断和及早干预、治疗是防止抑郁加重,降低围产期女性自杀率,减少不良妊娠结局的关键。中医药治疗PND疗效确切且优势明显,能克服西医治疗的不良反应和毒副作用,具有良好的应用前景。本文通过疏理文献对PND发生的危险因素及中医药治疗进展做一综述,以期为预防PND的发生及临床治疗提供科学依据。Perinatal depression (PND) is a prevalent mental disorder among women during the perinatal period, significantly impacting the physical and mental health of both women and their offspring. The onset of PND is associated with a variety of factors including women’s physiology, psychology, economics, and societal influences, but the pathogenesis remains incompletely understood. Early diagnosis, intervention and treatment are crucial in preventing the worsening of depression, reducing the suicide rate among perinatal women, and mitigating adverse pregnancy outcomes. Traditional Chinese medicine (TCM) has exhibited definitive efficacy and advantages in treating PND, which overcomes the adverse reactions and toxic effects of Western medicine and presents promising application prospects. This article presents a comprehensive review of the risk factors for PND and the advancements in TCM treatment, to provide a scientific basis for the prevention and clinical treatment of PND.展开更多
文摘围产期抑郁症(PND)是女性围产期内经历的精神障碍性疾病,严重威胁孕产妇及子代身心健康。PND的发生与女性生理、心理、经济和社会等多因素综合作用相关,发病机制尚不完全清楚。早期诊断和及早干预、治疗是防止抑郁加重,降低围产期女性自杀率,减少不良妊娠结局的关键。中医药治疗PND疗效确切且优势明显,能克服西医治疗的不良反应和毒副作用,具有良好的应用前景。本文通过疏理文献对PND发生的危险因素及中医药治疗进展做一综述,以期为预防PND的发生及临床治疗提供科学依据。Perinatal depression (PND) is a prevalent mental disorder among women during the perinatal period, significantly impacting the physical and mental health of both women and their offspring. The onset of PND is associated with a variety of factors including women’s physiology, psychology, economics, and societal influences, but the pathogenesis remains incompletely understood. Early diagnosis, intervention and treatment are crucial in preventing the worsening of depression, reducing the suicide rate among perinatal women, and mitigating adverse pregnancy outcomes. Traditional Chinese medicine (TCM) has exhibited definitive efficacy and advantages in treating PND, which overcomes the adverse reactions and toxic effects of Western medicine and presents promising application prospects. This article presents a comprehensive review of the risk factors for PND and the advancements in TCM treatment, to provide a scientific basis for the prevention and clinical treatment of PND.
文摘随着人们生活方式和饮食结构的变化,脂肪肝、糖尿病和肥胖症等代谢性疾病的患病率显著上升,严重危害了居民的身心健康,探究健康、普适和科学的饮食模式已然成为了现如今社会各界重点关注的议题。限时饮食(time-restricted eating,TRE)是一种限制每日进食时间的饮食模式,通常将每日进食时间限制在4~12 h,以延长处于禁食状态的时间,因其在减轻体重、改善葡萄糖耐量和调控代谢紊乱等方面的益处而受到了广泛的推崇。因此,该文通过中国知网、PubMed、Web of Science和世界卫生组织等官网与相关数据库,检索并梳理相关文献资料,对TRE促进代谢健康的临床证据及潜在机制进行分析并提出展望,以期为TRE在防治代谢性疾病领域中的应用提供一定的参考。