目的探究自拟活血祛风方结合针刺治疗周围性面瘫的临床效果。方法选取2020年3月—2021年3月江西省铅山县人民医院收治的60例周围性面瘫患者,随机分为治疗组和对照组,每组30例。对照组施行常规神经内科治疗和针刺治疗,治疗组施行常规神...目的探究自拟活血祛风方结合针刺治疗周围性面瘫的临床效果。方法选取2020年3月—2021年3月江西省铅山县人民医院收治的60例周围性面瘫患者,随机分为治疗组和对照组,每组30例。对照组施行常规神经内科治疗和针刺治疗,治疗组施行常规神经内科+针刺+自拟活血祛风方治疗。比较2组患者的治疗效果、面神经House-Brackmann分级情况、面神经功能评分、面部残疾指数躯体功能(Facial disability index physical,FDIP)、面部残疾指数社会功能(Facial disability index social,FDIS)及不良反应总发生率。结果治疗组的治疗总有效率高于对照组,差异有统计学意义(P<0.05);治疗组治疗后的面神经House-Brackmann分级情况优于对照组,差异有统计学意义(P<0.05);治疗组治疗后的面神经功能评分高于对照组,差异有统计学意义(P<0.001);治疗组治疗后的FDIP评分高于对照组,FDIS评分低于对照组,差异有统计学意义(P<0.001);2组患者的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论自拟活血祛风方结合针刺治疗周围性面瘫,能提高临床治疗效果,改善面神经功能,降低不良反应总发生率,值得临床推广应用。展开更多
New cyclodextrin derivatives （CDs）, heptakis（2, 6-di- O-methyl-3- O-methoxymethyl）-β-CD （ Ⅰ ） and heptakis（2, 3, 6-tri-O-methoxymethyl）-β-CD （ Ⅱ ）, were investigated for their chromatographic performance...New cyclodextrin derivatives （CDs）, heptakis（2, 6-di- O-methyl-3- O-methoxymethyl）-β-CD （ Ⅰ ） and heptakis（2, 3, 6-tri-O-methoxymethyl）-β-CD （ Ⅱ ）, were investigated for their chromatographic performance as stationary phases for capillary gas chromatography （CGC）. Both of the CDs exhibited good selectivity and satisfactory separation for test mixtures and aromatic positional isomers, and volatile compounds from Ligusticurn chuanxiong Hort. Additionally, the selectivity and elution orders of major compounds were compared with a well-recognized commercial column on the basis of the results by gas chromatography-mass spectrometry （GC-MS）. The present work demonstrates the good selectivity of the two new CDs and can be used as GC stationary phases for the separation of positional isomers and analytes in complex samples.展开更多
文摘目的探究自拟活血祛风方结合针刺治疗周围性面瘫的临床效果。方法选取2020年3月—2021年3月江西省铅山县人民医院收治的60例周围性面瘫患者,随机分为治疗组和对照组,每组30例。对照组施行常规神经内科治疗和针刺治疗,治疗组施行常规神经内科+针刺+自拟活血祛风方治疗。比较2组患者的治疗效果、面神经House-Brackmann分级情况、面神经功能评分、面部残疾指数躯体功能(Facial disability index physical,FDIP)、面部残疾指数社会功能(Facial disability index social,FDIS)及不良反应总发生率。结果治疗组的治疗总有效率高于对照组,差异有统计学意义(P<0.05);治疗组治疗后的面神经House-Brackmann分级情况优于对照组,差异有统计学意义(P<0.05);治疗组治疗后的面神经功能评分高于对照组,差异有统计学意义(P<0.001);治疗组治疗后的FDIP评分高于对照组,FDIS评分低于对照组,差异有统计学意义(P<0.001);2组患者的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论自拟活血祛风方结合针刺治疗周围性面瘫,能提高临床治疗效果,改善面神经功能,降低不良反应总发生率,值得临床推广应用。
文摘New cyclodextrin derivatives （CDs）, heptakis（2, 6-di- O-methyl-3- O-methoxymethyl）-β-CD （ Ⅰ ） and heptakis（2, 3, 6-tri-O-methoxymethyl）-β-CD （ Ⅱ ）, were investigated for their chromatographic performance as stationary phases for capillary gas chromatography （CGC）. Both of the CDs exhibited good selectivity and satisfactory separation for test mixtures and aromatic positional isomers, and volatile compounds from Ligusticurn chuanxiong Hort. Additionally, the selectivity and elution orders of major compounds were compared with a well-recognized commercial column on the basis of the results by gas chromatography-mass spectrometry （GC-MS）. The present work demonstrates the good selectivity of the two new CDs and can be used as GC stationary phases for the separation of positional isomers and analytes in complex samples.
