基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB29030104)the National Natural Science Foundation of China (31870731, 31971129)+3 种基金the Fundamental Research Funds for the Central Universities (WK9100000001)USTC New Medicine Joint Fund Training Program(WK9110000136)China Postdoctoral Science Foundation(2020M670084ZX)Hefei Comprehensive National Science Center (BJ9100000005)。