The effect of Radix Salviae Miltiorrhizae(RSM 丹参),a commonly used herbal blood cir-culation invigorator for the treatment of blood stasis(活血化瘀药)in traditional Chinesemedicine,on the duration of allograft surviv...The effect of Radix Salviae Miltiorrhizae(RSM 丹参),a commonly used herbal blood cir-culation invigorator for the treatment of blood stasis(活血化瘀药)in traditional Chinesemedicine,on the duration of allograft survival following heterotopic heart transplantation inexperimental animals was observed.The results in three heart transplantation models—auricular free graft in mice,abdominal graft in rats and cervical graft in rabbits—suggestedthat RSM injection in an appropriate dosage prolonged the survival time of cardiacallograft.The herb showed no significant toxicity.It was also found that RSM injection hada synergic effect with corticosteroids against graft rejection.展开更多
雌性大鼠20只,自每只盆腔二侧分别取出脂肪0.6 g 或1.2 g 一块,一块剪成2 mm 大小后注入左背皮下,另一块整块植入右背部皮下。随机分4组,分别观察3、6、12、24周。24周时,左侧为原重的21.1％,右侧为6.9％,左侧优于右侧(P<0.05)。镜...雌性大鼠20只,自每只盆腔二侧分别取出脂肪0.6 g 或1.2 g 一块,一块剪成2 mm 大小后注入左背皮下,另一块整块植入右背部皮下。随机分4组,分别观察3、6、12、24周。24周时,左侧为原重的21.1％,右侧为6.9％,左侧优于右侧(P<0.05)。镜下显示随时间延长,脂肪组织坏死灶逐渐扩大,并形成较大囊肿,新鲜囊肿边缘为残存的脂肪细胞,陈旧者被纤维细胞包围,囊内空虚,纤维间隔和包膜随时间延长而增厚。临床应用取自下颌和腹部等部位的皮下脂肪,剪成2～3 mm 后注入眉间、鼻唇沟等凹陷处,共15例27个部位。随访6个月,51.9％较满意,18.5％尚可,29.6％无效同注射前。展开更多
文摘The effect of Radix Salviae Miltiorrhizae(RSM 丹参),a commonly used herbal blood cir-culation invigorator for the treatment of blood stasis(活血化瘀药)in traditional Chinesemedicine,on the duration of allograft survival following heterotopic heart transplantation inexperimental animals was observed.The results in three heart transplantation models—auricular free graft in mice,abdominal graft in rats and cervical graft in rabbits—suggestedthat RSM injection in an appropriate dosage prolonged the survival time of cardiacallograft.The herb showed no significant toxicity.It was also found that RSM injection hada synergic effect with corticosteroids against graft rejection.
文摘雌性大鼠20只,自每只盆腔二侧分别取出脂肪0.6 g 或1.2 g 一块,一块剪成2 mm 大小后注入左背皮下,另一块整块植入右背部皮下。随机分4组,分别观察3、6、12、24周。24周时,左侧为原重的21.1％,右侧为6.9％,左侧优于右侧(P<0.05)。镜下显示随时间延长,脂肪组织坏死灶逐渐扩大,并形成较大囊肿,新鲜囊肿边缘为残存的脂肪细胞,陈旧者被纤维细胞包围,囊内空虚,纤维间隔和包膜随时间延长而增厚。临床应用取自下颌和腹部等部位的皮下脂肪,剪成2～3 mm 后注入眉间、鼻唇沟等凹陷处,共15例27个部位。随访6个月,51.9％较满意,18.5％尚可,29.6％无效同注射前。
