目的评价基于雷替曲塞或5-氟尿嘧啶(5-FU)治疗胃肠道肿瘤肝转移的疗效和安全性。方法检索万方、维普、知网、浙江大学图书馆、Cochrane图书馆、EMbase、Web of Science、PubMed、中国期刊全文数据库、中国生物医学文献数据库等,收集比...目的评价基于雷替曲塞或5-氟尿嘧啶(5-FU)治疗胃肠道肿瘤肝转移的疗效和安全性。方法检索万方、维普、知网、浙江大学图书馆、Cochrane图书馆、EMbase、Web of Science、PubMed、中国期刊全文数据库、中国生物医学文献数据库等,收集比较雷替曲塞联合化疗方案与5-FU联合化疗方案治疗胃肠道肿瘤肝转移的随机对照试验(RCTs),检索时间范围从各数据库建立至2021年11月,按纳入与排除标准由2名研究负责人提取所需数据且交叉核对,建表记录各项风险偏倚后评估,应用ReviewMan 5.3软件进行Meta分析。结果纳入14篇RCTs,涉及患者942例,试验组491例,对照组451例。Meta分析结果为试验组相较对照组疗效:总有效率的RR值为1.55(95%CI:1.34~1.80),临床获益率的RR值为1.19(95%CI:1.07~1.33)。安全性:恶心呕吐的RR值为0.80(95%CI:0.67~0.95),转氨酶升高的RR值为1.28(95%CI:1.07~1.53),白细胞减少的RR值为0.83(95%CI:0.65~1.05)。结论基于雷替曲塞联合化疗方案相对基于5-FU联合化疗方案疗效更佳,安全性高且耐受,适用于胃肠道肿瘤肝转移患者的治疗。展开更多
Environmental friendliness has become a dominant trend intextile production and a criterion for measuring the productionprocess and product quality of the dyeing and finishing industry.The article introduces some envi...Environmental friendliness has become a dominant trend intextile production and a criterion for measuring the productionprocess and product quality of the dyeing and finishing industry.The article introduces some environmental-friendly productspresented by some world leading textile chemicals producers onthe 4th China International Dye Industry, Pigments, Printingand Dyeing Auxiliary Exhibition. It points out that China is ahuge market for textile chemicals and Chinese textile chemicalproducers should improve the competitiveness of their products,so as to get foothold on this market.展开更多
文摘目的评价基于雷替曲塞或5-氟尿嘧啶(5-FU)治疗胃肠道肿瘤肝转移的疗效和安全性。方法检索万方、维普、知网、浙江大学图书馆、Cochrane图书馆、EMbase、Web of Science、PubMed、中国期刊全文数据库、中国生物医学文献数据库等,收集比较雷替曲塞联合化疗方案与5-FU联合化疗方案治疗胃肠道肿瘤肝转移的随机对照试验(RCTs),检索时间范围从各数据库建立至2021年11月,按纳入与排除标准由2名研究负责人提取所需数据且交叉核对,建表记录各项风险偏倚后评估,应用ReviewMan 5.3软件进行Meta分析。结果纳入14篇RCTs,涉及患者942例,试验组491例,对照组451例。Meta分析结果为试验组相较对照组疗效:总有效率的RR值为1.55(95%CI:1.34~1.80),临床获益率的RR值为1.19(95%CI:1.07~1.33)。安全性:恶心呕吐的RR值为0.80(95%CI:0.67~0.95),转氨酶升高的RR值为1.28(95%CI:1.07~1.53),白细胞减少的RR值为0.83(95%CI:0.65~1.05)。结论基于雷替曲塞联合化疗方案相对基于5-FU联合化疗方案疗效更佳,安全性高且耐受,适用于胃肠道肿瘤肝转移患者的治疗。
文摘Environmental friendliness has become a dominant trend intextile production and a criterion for measuring the productionprocess and product quality of the dyeing and finishing industry.The article introduces some environmental-friendly productspresented by some world leading textile chemicals producers onthe 4th China International Dye Industry, Pigments, Printingand Dyeing Auxiliary Exhibition. It points out that China is ahuge market for textile chemicals and Chinese textile chemicalproducers should improve the competitiveness of their products,so as to get foothold on this market.