广东佛山地区小儿脑性瘫痪患病率的抽样调查

脑性瘫痪（以下简称脑瘫）是由发育不成熟的大脑先天性发育缺陷或获得性（早产、低出生体重等）非进行性脑损伤所致,主要表现为运动障碍,伴或不伴有感知觉和智力缺陷。其脑部病理改变主要是脑部发育异常、脑部缺氧等引起的脑损伤[1-3]。许多国家和地区对脑瘫进行了较大规模的流行病学研究,结果显示脑瘫患病率在1‰~5‰范围之内。为给全省范围脑瘫流行病学调查打下基础,

井穴刺血对ACI大鼠PDGF、NSE的影响

目的探讨井穴刺血对急性脑缺血(ACI)大鼠神经功能、血清血小板衍生化生长因子(PDGF)、神经元特异化烯醇化酶(NSE)水平的影响。方法选择清洁级中老年Wistar大鼠150只,随机选取28只作为假手术组、其余122只大鼠采用经颞途径及其改良大脑中动脉阻断法建立ACI模型大鼠,选取建模成功的84只大鼠随机分为治疗组(井穴刺血处理)、空白对照组(不作处理)和西药组(腹腔注射尼莫地平处理)各28只,对比各组大鼠建模后3 h、24 h、72 h、7 d的神经功能评分、血清PDGF、NSE水平。结果造模后3h~造模后7d,空白对照组、西药组及治疗组的神经缺损功能评分显著的高于假手术组(P<0.05);造模后24h~造模后7d,西药组和治疗组大鼠的神经缺损功能评分均显著的低于空白对照组(P<0.05),西药组大鼠的神经缺损功能评分均显著的低于治疗组(P<0.05);造模后3h~造模后7d,空白对照组、西药组及治疗组的血清NSE、PDGF显著的高于假手术组(P<0.05);造模后3h~造模后7d,西药组和治疗组大鼠的血清NSE、PDGF均显著的低于空白对照组(P<0.05),西药组大鼠的血清NSE、PDGF均显著的低于和治疗组(P<0.05)。结论井穴刺血对ACI大鼠具有一定的神经保护作用,可有效降低血清中NSE及PDGF水平。

Meta-Analysis on scalp acupuncture based therapy in treating children cerebral palsy

Objective To explore the effectiveness of applying scalp acupuncture in treating child cerebral palsy. Method Computer was adopt to retrieve relevant literature about scalp acupuncture based therapy in treating children cerebral palsy published during 2999-2024 in PubMed, China National Knowledge Infrastructure （CNKI）, China Biology Medicine Disc （CBM）, VIP database, Wan fang database, Longyuan Electronic Journal and People＇s University Copying Periodical Resources Full-Text Database. The quality of literature about scalp acupuncture based therapy in treating children cerebral palsy was systematically evaluated and Meta analysis was conducted for integrated data by adopting evidence-based medicine and bibliometrics and through RevMan 5.2 statistical software. Results Two hundred and thirty-four literature were retrieved in total, within which, 7 of them were included. There were 796 cases in included literature, which were divided into a treatment group （416 cases） and a control group （380 cases）. The total effective cases in the treatment group was 378, with the total effective rate of 90.9%, and the total effective cases of the control group was 282, with the total effective rate of 73.9%, which could provide evidence for the fact that the treatment of scalp acupuncture has increased the effective rate of child cerebral palsy by 17%. It is shown by Meta analysis that： OR is 0.16, 95% CI is （0.22, 0.22） and combined effect test is Z=6.27, P〈0.02, indicating that the combined effect size of several studies included is of statistical significance, and the difference between the control group and the treatment group is statistically significant. Conclusion The total effective rate of scalp acupuncture based therapy in treating children cerebral palsy is higher than that of modern medicine comprehensive rehabilitation treatment, and the treatment method of scalp acupuncture could be widely applied to clinic; but since articles about scalp acupuncture based therapy in treating children cerebral palsy published domestically are not qualified enough, only a few literature are included, hence, more power and strong evidences shall be verified by literature with higher quality.

激光针灸治疗精神发育迟缓伴语言障碍研究

目的观察激光针灸治疗对精神发育迟缓患儿语言障碍的临床疗效。方法选取2013年10月至2014年10月于广州中医药大学附属南海妇产儿童医院康复中心住院的精神发育迟缓伴语言障碍患儿40例,按随机数字表分为治疗组和对照组各20例,治疗组在基本康复结合语言训练治疗的基础上加用激光针灸,对照组用基本康复结合语言训练治疗,隔日1次,20 d为1个疗程,每个疗程之间休息15 d,连续观察3个疗程,治疗前后均进行北京Gesell语言发育商评分(Gesell语言DQ)。数据的统计分析采用SPSS19.0统计学软件。总有效率比较采用x2检验;治疗前后Gesell语言DQ为计量资料,以±s表示。组内治疗前后比较采用配对样本t检验,组间比较采用两独立样本t检验,以P<0.05为差异有统计学意义。结果治疗组显效5例,有效12例,有效率为85%(17/20),对照组显效4例,有效7例,有效率为55%(11/20),两组治疗前后有效率比较,差异有统计学意义(x2=4.28,P=0.04);治疗后治疗组Gesell语言DQ优于对照组,差异有统计学意义(t=2.51,P=0.02)。结论激光针灸治疗精神发育迟缓患儿语言障碍疗效较好,值得临床推广。