Alpha-glucosidase inhibitors were screened from organic solvent extracts of macroalgae by a spec- trophotometrical method with p-nitrophenyl-D-glucopyranosidase as the substrate. The result indicates that or- ganic cr...Alpha-glucosidase inhibitors were screened from organic solvent extracts of macroalgae by a spec- trophotometrical method with p-nitrophenyl-D-glucopyranosidase as the substrate. The result indicates that or- ganic crude extracts from some macroalgae such as Rhodomela confervoides (Huds.) Silva, Gracilaria textorii (Suringar) DeToni, Plocamium telfairiae Harv., Dictyopteris divaricata (Okam.) Okam, Ulval pertusa and En- teromorpha intestinalis (L.) Link et al. show strong inhibitory activity of alpha-glucosidase at concentration of 79.6 μg/ml.展开更多
Apostichopus japonicus Selenka is an ideal tonic food that is used traditionally in many Asian countries, and it contains many bioactive substances, such as antioxidant, antimicrobial, and anticancer materials. To con...Apostichopus japonicus Selenka is an ideal tonic food that is used traditionally in many Asian countries, and it contains many bioactive substances, such as antioxidant, antimicrobial, and anticancer materials. To convert waste liquid generated during production into a useful resource, extract from waste liquid was isolated by column chromatography and studied by the pyrogallol autoxidation and 1,10-phenanthroline-Fe 2+ oxidation methods. Results show that the extract scavenged about 91% of the superoxide anion radical at a concentration of 1.4 mg/mL and 24% of the hydroxyl radical at 3.3 mg/mL. Four compounds were isolated and identified from the extract:2,4-dihydroxy-5-methyl-1,3-azine;2,4-dihydroxy- 1,3-diazine;3-O-[β-D-quinovopranosyl-(1 2)-4-O-sodium sulfate-β-D-xylopranosyl]-holosta-9(11)-ene- 3β,12α,17α-triol; and 24-ethyl-5α-cholesta-7-ene-3β-O-β-D-xylopyranoside. All of these compounds are known in A. japonicus, and were found in the waste liquid for the first time.展开更多
Known only in phaeophyceae, phlorotannins (brown algal polyphenols) are natural products with potential uses in pharmacology. This study yielded an extraction procedure to obtain high purity,high purity, high molecula...Known only in phaeophyceae, phlorotannins (brown algal polyphenols) are natural products with potential uses in pharmacology. This study yielded an extraction procedure to obtain high purity,high purity, high molecular weight phlorotannins from Sargassum kjellmanianum, and revealed the characteristics of their infrared and flourescence spectra. The antioxidative activity of phlorotannins, which was about 2.6 times as strongas that of 0.02% BHT (tert - butyl - 4 - hydroxytoluen). showed potential for preventing oil rancidification.展开更多
基金This work was supported by The Pilot Project of Knowledge Innovation Program of Institute of Oceanology, Chinese Academy of Sciences (L410225102)
文摘Alpha-glucosidase inhibitors were screened from organic solvent extracts of macroalgae by a spec- trophotometrical method with p-nitrophenyl-D-glucopyranosidase as the substrate. The result indicates that or- ganic crude extracts from some macroalgae such as Rhodomela confervoides (Huds.) Silva, Gracilaria textorii (Suringar) DeToni, Plocamium telfairiae Harv., Dictyopteris divaricata (Okam.) Okam, Ulval pertusa and En- teromorpha intestinalis (L.) Link et al. show strong inhibitory activity of alpha-glucosidase at concentration of 79.6 μg/ml.
基金Supported by the National Special Research Fund for Non-Profit Sector(Ocean)(No.201205025-5)
文摘Apostichopus japonicus Selenka is an ideal tonic food that is used traditionally in many Asian countries, and it contains many bioactive substances, such as antioxidant, antimicrobial, and anticancer materials. To convert waste liquid generated during production into a useful resource, extract from waste liquid was isolated by column chromatography and studied by the pyrogallol autoxidation and 1,10-phenanthroline-Fe 2+ oxidation methods. Results show that the extract scavenged about 91% of the superoxide anion radical at a concentration of 1.4 mg/mL and 24% of the hydroxyl radical at 3.3 mg/mL. Four compounds were isolated and identified from the extract:2,4-dihydroxy-5-methyl-1,3-azine;2,4-dihydroxy- 1,3-diazine;3-O-[β-D-quinovopranosyl-(1 2)-4-O-sodium sulfate-β-D-xylopranosyl]-holosta-9(11)-ene- 3β,12α,17α-triol; and 24-ethyl-5α-cholesta-7-ene-3β-O-β-D-xylopyranoside. All of these compounds are known in A. japonicus, and were found in the waste liquid for the first time.
文摘Known only in phaeophyceae, phlorotannins (brown algal polyphenols) are natural products with potential uses in pharmacology. This study yielded an extraction procedure to obtain high purity,high purity, high molecular weight phlorotannins from Sargassum kjellmanianum, and revealed the characteristics of their infrared and flourescence spectra. The antioxidative activity of phlorotannins, which was about 2.6 times as strongas that of 0.02% BHT (tert - butyl - 4 - hydroxytoluen). showed potential for preventing oil rancidification.
