In addition to (±)-4-methyl-6-isobutenyl-3,4,5,6-tetrahydro-4H-pyran with many available synthetic sequences, (±)-4-methyl-6-isobutenyl-5, 6-dihydro-2H-pyran (nerol oxide, 1) and (±)-2(1’-methylvinyl)-...In addition to (±)-4-methyl-6-isobutenyl-3,4,5,6-tetrahydro-4H-pyran with many available synthetic sequences, (±)-4-methyl-6-isobutenyl-5, 6-dihydro-2H-pyran (nerol oxide, 1) and (±)-2(1’-methylvinyl)-5-methyl-5-vinyltetrahydrofuran (desoxide, 2) are the important principals of natural rose oil. Only a report concerning the syntheses of and has appeared so far in Ref. [3]. Rose bengal sensitized photooxidation of nerol, followed by reduction and dilute acid catalyzed cyclolization gave and simultaneously, thus, it was suggested that both and were derived from the same precursor, nerol, in the plant. Here we wish to report a new synthetic route of the title perfume compounds with an abundant domestic resource, lina-展开更多
基金Project supported by the National Natural Science Foundation of China.
文摘In addition to (±)-4-methyl-6-isobutenyl-3,4,5,6-tetrahydro-4H-pyran with many available synthetic sequences, (±)-4-methyl-6-isobutenyl-5, 6-dihydro-2H-pyran (nerol oxide, 1) and (±)-2(1’-methylvinyl)-5-methyl-5-vinyltetrahydrofuran (desoxide, 2) are the important principals of natural rose oil. Only a report concerning the syntheses of and has appeared so far in Ref. [3]. Rose bengal sensitized photooxidation of nerol, followed by reduction and dilute acid catalyzed cyclolization gave and simultaneously, thus, it was suggested that both and were derived from the same precursor, nerol, in the plant. Here we wish to report a new synthetic route of the title perfume compounds with an abundant domestic resource, lina-
