In order to find new anticonvulsant compounds,we design and synthesis the derivatives of norcantharidin.The structures of the eight target compounds are identified by IR,1H-NMR and HR-MS,and the reaction conditions ar...In order to find new anticonvulsant compounds,we design and synthesis the derivatives of norcantharidin.The structures of the eight target compounds are identified by IR,1H-NMR and HR-MS,and the reaction conditions are optimized.展开更多
In order to find new anticonvulsant compounds,eight norcantharidin-glycine-substituted phenylthiourea compounds were designed and synthesized.The structures of the eight target compounds were identified by IR,1H-NMR a...In order to find new anticonvulsant compounds,eight norcantharidin-glycine-substituted phenylthiourea compounds were designed and synthesized.The structures of the eight target compounds were identified by IR,1H-NMR and HR-MS.Preliminary test of anticonvulsant activity showed that compounds d7 and d8 had appreciable antiepileptic activity.展开更多
文摘In order to find new anticonvulsant compounds,we design and synthesis the derivatives of norcantharidin.The structures of the eight target compounds are identified by IR,1H-NMR and HR-MS,and the reaction conditions are optimized.
文摘In order to find new anticonvulsant compounds,eight norcantharidin-glycine-substituted phenylthiourea compounds were designed and synthesized.The structures of the eight target compounds were identified by IR,1H-NMR and HR-MS.Preliminary test of anticonvulsant activity showed that compounds d7 and d8 had appreciable antiepileptic activity.
