As a novel type of B cell that expands with increasing age,which was first observed in 2011[1,2],age-associated B cells(ABCs)are becoming a hotspot area in the field of immunology.More importantly,ABCs accumulate prog...As a novel type of B cell that expands with increasing age,which was first observed in 2011[1,2],age-associated B cells(ABCs)are becoming a hotspot area in the field of immunology.More importantly,ABCs accumulate progressively in chronic inflammatory states such as autoimmunity,chronic infection,and aging,and are closely associated with developing autoimmune diseases[3].展开更多
基金supported by Ministry of Science and Technology of China(2021YFC2300500,2021YFC2302403)the National Natural Science Foundation of China(32141004,81825010).
文摘As a novel type of B cell that expands with increasing age,which was first observed in 2011[1,2],age-associated B cells(ABCs)are becoming a hotspot area in the field of immunology.More importantly,ABCs accumulate progressively in chronic inflammatory states such as autoimmunity,chronic infection,and aging,and are closely associated with developing autoimmune diseases[3].