布鲁氏菌病是由布氏杆菌引起的一种严重的人畜共患传染的变态反应性疾病,该病是一种全身性疾病,可累及多个器官,具有传染性强,传播范围广的特点。布鲁氏菌性脊柱炎(brucellar spondylitis)是布氏杆菌侵犯脊柱导致的感染性脊柱炎性疾病,...布鲁氏菌病是由布氏杆菌引起的一种严重的人畜共患传染的变态反应性疾病,该病是一种全身性疾病,可累及多个器官,具有传染性强,传播范围广的特点。布鲁氏菌性脊柱炎(brucellar spondylitis)是布氏杆菌侵犯脊柱导致的感染性脊柱炎性疾病,其主要临床表现为顽固性腰痛、局部压痛叩击痛、发热、多汗、全身乏力、肝、脾及淋巴结肿大等症状,若影响神经可出现下肢的疼痛和麻木,甚至有可能截瘫。临床中对该病的诊断和治疗缺乏统一的认识,笔者回顾近年相关文献,对布鲁氏菌性脊柱炎的流行病学、临床表现、实验室检查、影像学表现,诊断标准、鉴别诊断及治疗进展综述如下。Brucellosis is a severe zoonotic allergic disease caused by Brucella, which is a systemic disease that can affect multiple organs and has the characteristics of strong contagiousness and wide spread. Brucella spondylitis is an infectious spinal inflammatory disease caused by Brucella invasion of the spine, the main clinical manifestations are intractable low back pain, local tenderness, percussion pain, fever, sweating, malaise, liver, spleen and lymph node swelling and other symptoms, if the nerves are affected, pain and numbness of the lower limbs may occur, and even paraplegia may occur. The author reviews the relevant literature in recent years, and reviews the epidemiology, clinical manifestations, laboratory tests, imaging findings, diagnostic criteria, differential diagnosis and treatment progress of Brucella spondylitis as follows.展开更多
文摘布鲁氏菌病是由布氏杆菌引起的一种严重的人畜共患传染的变态反应性疾病,该病是一种全身性疾病,可累及多个器官,具有传染性强,传播范围广的特点。布鲁氏菌性脊柱炎(brucellar spondylitis)是布氏杆菌侵犯脊柱导致的感染性脊柱炎性疾病,其主要临床表现为顽固性腰痛、局部压痛叩击痛、发热、多汗、全身乏力、肝、脾及淋巴结肿大等症状,若影响神经可出现下肢的疼痛和麻木,甚至有可能截瘫。临床中对该病的诊断和治疗缺乏统一的认识,笔者回顾近年相关文献,对布鲁氏菌性脊柱炎的流行病学、临床表现、实验室检查、影像学表现,诊断标准、鉴别诊断及治疗进展综述如下。Brucellosis is a severe zoonotic allergic disease caused by Brucella, which is a systemic disease that can affect multiple organs and has the characteristics of strong contagiousness and wide spread. Brucella spondylitis is an infectious spinal inflammatory disease caused by Brucella invasion of the spine, the main clinical manifestations are intractable low back pain, local tenderness, percussion pain, fever, sweating, malaise, liver, spleen and lymph node swelling and other symptoms, if the nerves are affected, pain and numbness of the lower limbs may occur, and even paraplegia may occur. The author reviews the relevant literature in recent years, and reviews the epidemiology, clinical manifestations, laboratory tests, imaging findings, diagnostic criteria, differential diagnosis and treatment progress of Brucella spondylitis as follows.