目的:应用定量脑电图(quantitative electroencephalogram,QEEG)δ+θ/α+β相对功率值、格拉斯哥昏迷评分(Glasgow coma scale,GCS)作为评价指标,来观察声刺激对脑外伤昏迷患者的促醒作用。方法:选择符合入选标准的40例颅脑外伤后昏迷...目的:应用定量脑电图(quantitative electroencephalogram,QEEG)δ+θ/α+β相对功率值、格拉斯哥昏迷评分(Glasgow coma scale,GCS)作为评价指标,来观察声刺激对脑外伤昏迷患者的促醒作用。方法:选择符合入选标准的40例颅脑外伤后昏迷患者。20例为在康复科、神经外科病房内,家属能够积极配合,有长期固定护理人员,经过正规声刺激疗法治疗的脑外伤昏迷患者(声刺激组);20例为在重症监护室内、康复科及神经外科病房内,家属配合度一般,经常更换护理人员,未经过正规声刺激治疗的脑外伤昏迷患者(对照组)。入组后跟踪观察1个月,比较两组患者GCS评分、δ+θ/α+β值有无差异。两组间除有无正规声刺激治疗外,余治疗无明显区别,且两组间在年龄、性别、外伤类型及病程等相匹配。结果:40例颅脑外伤昏迷患者中,声刺激组与对照组治疗后比较,GCS评分明显增大,有统计学差异(P<0.05)。声刺激组与对照组治疗后比较,δ+θ/α+β值明显减小,有统计学差异(P<0.05)。治疗前40例患者GCS评分为3~8分与δ+θ/α+β值呈负相关(r=-0.482,P=0.002,n=40),治疗后31例患者GCS评分为9~15分与δ+θ/α+β值呈负相关(r=-0.493,P=0.005,n=31)。结论:通过对δ+θ/α+β值及GCS评分的观察,说明声刺激法对颅脑外伤昏迷患者有明显的促醒作用。定量脑电图(δ+θ/α+β值)作为一种客观、量化的脑功能检测手段,对昏迷患者大脑功能状态的评估有重要的价值。展开更多
Metal halide perovskites have been regarded as remarkable materials for next-generation light-harvesting and light emission devices. Due to their unique optical properties, such as high absorption coefficient, high op...Metal halide perovskites have been regarded as remarkable materials for next-generation light-harvesting and light emission devices. Due to their unique optical properties, such as high absorption coefficient, high optical gain, low trappingstate density, and ease of band gap engineering, perovskites promise to be used in lasing devices. In this article, the recent progresses of microlasers based on reduced-dimensional structures including nanoplatelets, nanowires, and quantum dots are reviewed from both fundamental photophysics and device applications. Furthermore, perovskite-based plasmonic nanolasers and polariton lasers are summarized. Perspectives on perovskite-based small lasers are also discussed. This review can serve as an overview and evaluation of state-of-the-art micro/nanolaser science.展开更多
文摘目的:应用定量脑电图(quantitative electroencephalogram,QEEG)δ+θ/α+β相对功率值、格拉斯哥昏迷评分(Glasgow coma scale,GCS)作为评价指标,来观察声刺激对脑外伤昏迷患者的促醒作用。方法:选择符合入选标准的40例颅脑外伤后昏迷患者。20例为在康复科、神经外科病房内,家属能够积极配合,有长期固定护理人员,经过正规声刺激疗法治疗的脑外伤昏迷患者(声刺激组);20例为在重症监护室内、康复科及神经外科病房内,家属配合度一般,经常更换护理人员,未经过正规声刺激治疗的脑外伤昏迷患者(对照组)。入组后跟踪观察1个月,比较两组患者GCS评分、δ+θ/α+β值有无差异。两组间除有无正规声刺激治疗外,余治疗无明显区别,且两组间在年龄、性别、外伤类型及病程等相匹配。结果:40例颅脑外伤昏迷患者中,声刺激组与对照组治疗后比较,GCS评分明显增大,有统计学差异(P<0.05)。声刺激组与对照组治疗后比较,δ+θ/α+β值明显减小,有统计学差异(P<0.05)。治疗前40例患者GCS评分为3~8分与δ+θ/α+β值呈负相关(r=-0.482,P=0.002,n=40),治疗后31例患者GCS评分为9~15分与δ+θ/α+β值呈负相关(r=-0.493,P=0.005,n=31)。结论:通过对δ+θ/α+β值及GCS评分的观察,说明声刺激法对颅脑外伤昏迷患者有明显的促醒作用。定量脑电图(δ+θ/α+β值)作为一种客观、量化的脑功能检测手段,对昏迷患者大脑功能状态的评估有重要的价值。
基金Project supported by the National Key Research and Development Program of China(Grant Nos.2017YFA0304600,2017YFA0205700,and2016YFA0200700)the National Natural Science Foundation of China(Grant Nos.61774003 and 21673054)+2 种基金the Start-up Funding of Peking University,National Young 1000-talents Scholarship of Chinathe Open Research Fund Program of the State Key Laboratory of Low-Dimensional Quantum Physics,China(Grant No.KF201604)the Key Research Program of Frontier Sciences,Chinese Academy of Sciences(Grant No.QYZDB-SSW-SYS031)
文摘Metal halide perovskites have been regarded as remarkable materials for next-generation light-harvesting and light emission devices. Due to their unique optical properties, such as high absorption coefficient, high optical gain, low trappingstate density, and ease of band gap engineering, perovskites promise to be used in lasing devices. In this article, the recent progresses of microlasers based on reduced-dimensional structures including nanoplatelets, nanowires, and quantum dots are reviewed from both fundamental photophysics and device applications. Furthermore, perovskite-based plasmonic nanolasers and polariton lasers are summarized. Perspectives on perovskite-based small lasers are also discussed. This review can serve as an overview and evaluation of state-of-the-art micro/nanolaser science.
基金supported by the Ministry of Science and Technology(2016YFA0200700 and 2017YFA0205004)the National Natural Science Foundation of China(21673054,11874130,61307120,61704038 and 11474187)the Open Research Fund Program of the State Key Laboratory of Low-Dimensional Quantum Physics(KF201902)。
基金Ministry of Science and Technology (2017YFA0205004, 2016YFA0200700)the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB36000000)+2 种基金the National Natural Science Foundation of China (61704038, 21673054, 11874130, 12074086, 61307120, 61704038 and 11474187)the Open Research Fund Program of the State Key Laboratory of Low-Dimensional Quantum Physics (KF201902)the CAS Instrument Development Project (Y950291) for their support。
