目的探讨鸢尾素、瘦素水平对绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)的预测价值。方法收集2019年11月~2021年1月于广州中医药大学第三附属医院门诊就诊的64例绝经女性作为研究对象,分为骨质疏松组(n=33)和非骨质疏松组(n=3...目的探讨鸢尾素、瘦素水平对绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)的预测价值。方法收集2019年11月~2021年1月于广州中医药大学第三附属医院门诊就诊的64例绝经女性作为研究对象,分为骨质疏松组(n=33)和非骨质疏松组(n=31),比较两组受试者基线资料及鸢尾素、瘦素水平;采用Pearson相关性分析研究鸢尾素、瘦素水平与基线资料之间的相关性;采用受试者工作特征(receiver operating characteristic,ROC)曲线评价鸢尾素、瘦素对PMOP的预测效能。结果骨质疏松组的鸢尾素、瘦素水平均低于非骨质疏松组,差异有统计学意义(P<0.01);Pearson相关性分析结果显示,鸢尾素、瘦素水平与腰椎骨密度、整体骨密度均呈显著正相关(P<0.01);ROC曲线分析结果显示,鸢尾素的曲线下面积(area under the curve,AUC)为0.706,瘦素的AUC为0.702;并确定了两者的预测临界值:鸢尾素水平>224.88pg/ml,敏感度为58.06%,特异性为87.91%;瘦素水平>13.93μg/L,敏感度为61.29%,特异性为78.79%。结论鸢尾素、瘦素水平对PMOP具有良好的预测价值;绝经后女性血清鸢尾素水平<224.88pg/ml、瘦素水平<13.93μg/L,可能存在着骨量丢失的可能。展开更多
Using the semiclassical ensemble model,the dependence of relative amplitude for the recollision dynamics in nonsequential double ionization(NSDI)of neon atom driven by the orthogonally polarized two-color field(OTC)la...Using the semiclassical ensemble model,the dependence of relative amplitude for the recollision dynamics in nonsequential double ionization(NSDI)of neon atom driven by the orthogonally polarized two-color field(OTC)laser field is theoretically studied.And the dynamics in two typical collision pathways,recollision-impact-ionization(RII)and recollisionexcitation with subsequent ionization(RESI),is systematically explored.Our results reveal that the V-shaped structure in the correlated momentum distribution is mainly caused by the RII mechanism when the relative amplitude of the OTC laser field is zero,and the first ionized electrons will quickly skim through the nucleus and share few energy with the second electron.As the relative amplitude increases,the V-shaped structure gradually disappears and electrons are concentrated on the diagonal in the electron correlation spectrum,indicating that the energy sharing after electrons collision is symmetric for OTC laser fields with large relative amplitudes.Our studies show that changing the relative amplitude of the OTC laser field can efficiently control the electron–electron collisions and energy exchange efficiency in the NSDI process.展开更多
文摘目的探讨鸢尾素、瘦素水平对绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)的预测价值。方法收集2019年11月~2021年1月于广州中医药大学第三附属医院门诊就诊的64例绝经女性作为研究对象,分为骨质疏松组(n=33)和非骨质疏松组(n=31),比较两组受试者基线资料及鸢尾素、瘦素水平;采用Pearson相关性分析研究鸢尾素、瘦素水平与基线资料之间的相关性;采用受试者工作特征(receiver operating characteristic,ROC)曲线评价鸢尾素、瘦素对PMOP的预测效能。结果骨质疏松组的鸢尾素、瘦素水平均低于非骨质疏松组,差异有统计学意义(P<0.01);Pearson相关性分析结果显示,鸢尾素、瘦素水平与腰椎骨密度、整体骨密度均呈显著正相关(P<0.01);ROC曲线分析结果显示,鸢尾素的曲线下面积(area under the curve,AUC)为0.706,瘦素的AUC为0.702;并确定了两者的预测临界值:鸢尾素水平>224.88pg/ml,敏感度为58.06%,特异性为87.91%;瘦素水平>13.93μg/L,敏感度为61.29%,特异性为78.79%。结论鸢尾素、瘦素水平对PMOP具有良好的预测价值;绝经后女性血清鸢尾素水平<224.88pg/ml、瘦素水平<13.93μg/L,可能存在着骨量丢失的可能。
基金Project supported by the National Natural Science Foundation of China (Grant Nos.12204132 and 12304376)Excellent Youth Science Foundation of Shandong Province (Overseas) (Grant No.2022HWYQ-073)+1 种基金the Fundamental Research Funds for the Central Universities (Grant No.HIT.OCEF.2022042)Natural Science Foundation of Shandong Province (Grant No.ZR2023QA075)。
文摘Using the semiclassical ensemble model,the dependence of relative amplitude for the recollision dynamics in nonsequential double ionization(NSDI)of neon atom driven by the orthogonally polarized two-color field(OTC)laser field is theoretically studied.And the dynamics in two typical collision pathways,recollision-impact-ionization(RII)and recollisionexcitation with subsequent ionization(RESI),is systematically explored.Our results reveal that the V-shaped structure in the correlated momentum distribution is mainly caused by the RII mechanism when the relative amplitude of the OTC laser field is zero,and the first ionized electrons will quickly skim through the nucleus and share few energy with the second electron.As the relative amplitude increases,the V-shaped structure gradually disappears and electrons are concentrated on the diagonal in the electron correlation spectrum,indicating that the energy sharing after electrons collision is symmetric for OTC laser fields with large relative amplitudes.Our studies show that changing the relative amplitude of the OTC laser field can efficiently control the electron–electron collisions and energy exchange efficiency in the NSDI process.
