Serum testosterone concentration levels were measured in 27 female patients with ovarian masses and n 8 female patients with malignant gastrointestinal tumors. The serum testasterone levels were found to be a more spe...Serum testosterone concentration levels were measured in 27 female patients with ovarian masses and n 8 female patients with malignant gastrointestinal tumors. The serum testasterone levels were found to be a more specific marker,compared with other methods, in the differential diagnosis of primary and metastatic tumors(P<0.01).Serum testosterone was at abnormally high levels inpatients with Krukenberg tumors assoiated with signet cells and luteinized stroma cells, but fell to very low levels after oophoiectomy. Testosterone levels were normal showever in patients with poorly-differentiated metastatic ovarisn tumors, or with gastro-intestinal cancers not involving the ovaries.We also found that testosaterone levels in patients with mucinous adenocarcinoma of either ovary or of the gastro-intestinal tract were higher than in patients with other types of tumor(P<0.05).展开更多
文摘Serum testosterone concentration levels were measured in 27 female patients with ovarian masses and n 8 female patients with malignant gastrointestinal tumors. The serum testasterone levels were found to be a more specific marker,compared with other methods, in the differential diagnosis of primary and metastatic tumors(P<0.01).Serum testosterone was at abnormally high levels inpatients with Krukenberg tumors assoiated with signet cells and luteinized stroma cells, but fell to very low levels after oophoiectomy. Testosterone levels were normal showever in patients with poorly-differentiated metastatic ovarisn tumors, or with gastro-intestinal cancers not involving the ovaries.We also found that testosaterone levels in patients with mucinous adenocarcinoma of either ovary or of the gastro-intestinal tract were higher than in patients with other types of tumor(P<0.05).