P.A3679芽孢在竹笋汤汁中的耐热性试验

<正>梭状产芽孢杆菌Clostridium sporogenesputrefactive Anerobe3679(简称P．A3679 )是一种嗜温厌氧菌,最适生长温度30~40℃。

Enhanced sensing of anharmonicities in a gain-based anti-PT symmetric system

We study the enhanced sensing of weak anharmonicities in a gain-based cavity-magnon-waveguide coupled system.By dissipatively coupling the two subsystems through a mediating waveguide,the Hamiltonian of the system is tailored to be anti-parity-time symmetric.Unique to the gain condition,the eigenvalues exhibit two singularities with linewidth suppression,distinguishing them from those of gain-free systems.Under the gain condition,a counter-intuitive bistable signature emerges even at low drive powers.As the effective gain approaches a certain value,this bistability yields a significantly enhanced spin-current response of the magnon mode.Consequently,the sensitivity,quantified by an enhancement factor,is enhanced remarkably compared to the linewidth suppression scenario.Moreover,the high enhancement factor can be sustained over a broad gain-bandwidth and also stays large even when the coherent coupling becomes considerably strong.Based on the integrated cavity-magnon-waveguide systems,this scheme can be used for sensing different physical quantities related to the Kerr-type nonlinearity and has potential applications in high-precision measuring microwave-signal nonlinearities.

广州地区育龄人群地中海贫血基因分型及筛查漏检误诊的原因分析

目的:了解广州地区育龄人群的地中海贫血(简称:地贫)基因携带率及基因型分布特征,分析地贫筛查的漏检和误诊原因,为育龄地贫基因携带者进行人工辅助受孕提供依据。方法:收集2019年1月到2021年12月在我院生殖医学科就诊并同时进行地贫筛查及地贫基因检测的育龄患者31455例,分析其地贫相关实验室检查结果,包括红细胞参数、红细胞渗透脆性、血红蛋白电泳及地贫基因检测,计算地贫基因携带率,并通过比较筛查和基因检测结果找出漏筛和误诊病例。结果:共检出育龄地贫基因携带者4455例,地贫基因携带率为14.16%。其中,α-地中海贫血3365例,常见的基因型有^(--SEA)/αα、-α^(3.7)/αα和-α^(4.2)/αα;β-地中海贫血914例,常见的基因型有β^(CD41-42(-TCCT))/β^(N)、β^(IVS-2-654(C→T))/β^(N)和β^(-28(A→G))/β^(N);α-合并β-地中海贫血176例,最常见的基因型是β^(CD41-42(-TCCT))/β^(N)/^(--SEA)/αα。漏筛病例有731例,多为静止型α-地贫。误诊病例有4784例,其中有2701例误诊病例其红细胞渗透脆性和红细胞参数均正常,仅因HbA2<2.5%且HbA>97.5%被误诊为携带地贫基因。结论:广州地区的育龄人群具有较高的地贫基因携带率,静止型α-地贫容易在筛查中被漏检。