目的探讨针康法联合重复经颅磁刺激(Repeat transcranial magnetic stimulation,rTMS)治疗脑梗死后认知障碍的临床疗效价值。方法选取2020年4月—2022年6月期间黑龙江中医药大学附属第二医院收治的89例脑梗死后认知障碍患者作为试验对象...目的探讨针康法联合重复经颅磁刺激(Repeat transcranial magnetic stimulation,rTMS)治疗脑梗死后认知障碍的临床疗效价值。方法选取2020年4月—2022年6月期间黑龙江中医药大学附属第二医院收治的89例脑梗死后认知障碍患者作为试验对象,按随机数字表法分为西医组44例和针康组45例。两组患者均给予常规治疗与康复方案,在此基础上,西医组给予rTMS治疗,针康组给予rTMS+针康法治疗,两组患者均治疗4周。观察比较两组患者临床疗效、不良反应情况,治疗前后认知功能评分[简易智能精神状态检查量表(Mini-Mental State Examination,MMSE)、蒙特利尔认知量表(Montreal Cognitive Assessment,MoCA)]、血清血管新生指标[血管生成素-1(Angiopoietin-1,Ang-1)、血管生成素-2(Angiopoietin-2,Ang-2)、血管内皮生长因子(Vascular endothelial growth factor,VEGF)]水平及脑血流动力学指标(外周阻力、平均血流速度、平均血流量)变化。结果(1)临床疗效:针康组临床总有效率95.56%(43/45)高于西医组81.40%(35/43),差异有统计学意义(P<0.05)。(2)认知功能:治疗后两组患者MMSE评分、MoCA评分均较治疗前升高,差异有统计学意义(P<0.05);且针康组MMSE评分、MoCA评分较西医组明显升高,差异有统计学意义(P<0.05)。(3)血管新生指标:治疗后两组患者血清Ang-1、Ang-2及VEGF水平均较治疗前升高,差异有统计学意义(P<0.05);且针康组血清Ang-1、Ang-2及VEGF水平较西医组明显升高,差异有统计学意义(P<0.05)。(4)脑血流动力学:治疗后两组患者平均血流速度、平均血流量较治疗前升高,外周阻力较治疗前降低,差异有统计学意义(P<0.05);且针康组平均血流速度、平均血流量较西医组明显升高,外周阻力较西医组明显降低,差异有统计学意义(P<0.05)。(5)安全性:两组患者均未发生影响治疗的不良事件与不良反应。结论针康法联合rTMS治疗脑梗死后认知障碍效果显著、安全性高,有利于改善患者认知功能,可能与促进血管新生及改善脑血流动力学等机制有关。展开更多
In this Letter, we experimentally demonstrate a full-duplex transmission system of IEEE 802.11ac-compliant multiple-input multiple-output(MIMO) signals over a 2-km 7-core fiber for in-building wireless local-area netw...In this Letter, we experimentally demonstrate a full-duplex transmission system of IEEE 802.11ac-compliant multiple-input multiple-output(MIMO) signals over a 2-km 7-core fiber for in-building wireless local-area network(WLAN) distributed antenna systems. For full-duplex 3 × 3 MIMO demonstration, the crosstalk impacts of both fiber-transmission-only and optic-wireless transmission situation are evaluated. The results indicate that the impact of crosstalk on radio-over-fiber(ROF) link performance is not significant and the quality of the cascaded multi-core fiber and wireless channel is mainly determined by the wireless part. To further improve the system capacity, polarization multiplexing(PolMux) technology is employed to achieve a full-duplex 6 × 6MIMO over a single 7-core fiber. Although employing the PolMux method will slightly decrease the EVM and condition number performance as opposed to a non-PolMux MCF system, it is still a competitive solution in large optical connection demand scenarios that require a low cost.展开更多
A full-band direct-conversion receiver using a microwave photonic in-phase and quadrature(I/Q) mixer is proposed and experimentally evaluated in terms of radio frequency(RF) range, port isolation, phase imbalance,conv...A full-band direct-conversion receiver using a microwave photonic in-phase and quadrature(I/Q) mixer is proposed and experimentally evaluated in terms of radio frequency(RF) range, port isolation, phase imbalance,conversion gain, noise figure, spurious-free dynamic range, and error vector magnitude. The proposed microwave photonic I/Q mixer shows significant advantages in local oscillator leakage and I/Q phase imbalance over entire RF bands, which are recognized as major drawbacks of conventional direct-conversion receivers.展开更多
基金supported in part by the National Natural Science Foundation of China(Nos.61601049 and 61431003)the National 863 Program of China(No.2015AA016903)
文摘In this Letter, we experimentally demonstrate a full-duplex transmission system of IEEE 802.11ac-compliant multiple-input multiple-output(MIMO) signals over a 2-km 7-core fiber for in-building wireless local-area network(WLAN) distributed antenna systems. For full-duplex 3 × 3 MIMO demonstration, the crosstalk impacts of both fiber-transmission-only and optic-wireless transmission situation are evaluated. The results indicate that the impact of crosstalk on radio-over-fiber(ROF) link performance is not significant and the quality of the cascaded multi-core fiber and wireless channel is mainly determined by the wireless part. To further improve the system capacity, polarization multiplexing(PolMux) technology is employed to achieve a full-duplex 6 × 6MIMO over a single 7-core fiber. Although employing the PolMux method will slightly decrease the EVM and condition number performance as opposed to a non-PolMux MCF system, it is still a competitive solution in large optical connection demand scenarios that require a low cost.
基金supported in part by the National 863Program of China(No.2015AA016903)the National Natural Science Foundation of China(No.61431003,61601049,and 61401411)+1 种基金the Innovation Foundation of China Electronics Technology Group Corporation(CETC)the Innovation Foundation of Key Laboratory of Aerospace Information Applications at CETC
文摘A full-band direct-conversion receiver using a microwave photonic in-phase and quadrature(I/Q) mixer is proposed and experimentally evaluated in terms of radio frequency(RF) range, port isolation, phase imbalance,conversion gain, noise figure, spurious-free dynamic range, and error vector magnitude. The proposed microwave photonic I/Q mixer shows significant advantages in local oscillator leakage and I/Q phase imbalance over entire RF bands, which are recognized as major drawbacks of conventional direct-conversion receivers.