为提高多糖-蛋白混合物稳定性,改善彼此性能并探究制备过程中各因素对多糖-蛋白混合凝胶成型及性能的影响,以魔芋葡甘聚糖(konjac glucomannan,KGM)和大豆分离蛋白(soybean protein isolate,SPI)为试材,制成KGM-SPI混合凝胶,研究制备工...为提高多糖-蛋白混合物稳定性,改善彼此性能并探究制备过程中各因素对多糖-蛋白混合凝胶成型及性能的影响,以魔芋葡甘聚糖(konjac glucomannan,KGM)和大豆分离蛋白(soybean protein isolate,SPI)为试材,制成KGM-SPI混合凝胶,研究制备工艺对其凝胶强度和持水性的影响。在单因素试验的基础上,取KGM-SPI总质量分数、KGM与SPI配比、KCl浓度和Ca(OH)_2添加量为自变量,凝胶强度为响应值,建立混合凝胶强度的二次回归方程,并通过响应面分析得到优化制备条件为:KGM-SPI总质量分数4.5%、KGM与SPI配比3∶1、KCl浓度0.13 mol/L、Ca(OH)_2添加量0.15%。此条件下混合凝胶强度验证值为2.758 N,与预测值2.779 N相近。通过对优化前后凝胶质构特性进行了对比分析,均证实优化结果可靠。展开更多
目的系统评价灸法防治肿瘤放化疗后恶心呕吐的临床疗效与取穴规律,为灸法防治肿瘤放化疗后恶心呕吐提供临床证据。方法纳入中英文的文献,通过计算机检索中国知网(China National Knowledge Infrastructure,CNKI)数据库、中国生物医学文...目的系统评价灸法防治肿瘤放化疗后恶心呕吐的临床疗效与取穴规律,为灸法防治肿瘤放化疗后恶心呕吐提供临床证据。方法纳入中英文的文献,通过计算机检索中国知网(China National Knowledge Infrastructure,CNKI)数据库、中国生物医学文献数据库(China Biology Medicine disc,CBM)、万方数据库、维普、Cochrane library、Embase、Pubmed。以灸法防治肿瘤放化疗后恶心呕吐的随机对照试验(Randomized controlled trial,RCT)为研究对象,由2名研究员独立进行文献筛选、资料提取以及文献的质量评价,再运用Revman 5.3进行Meta分析。结果最终纳入13篇文献,共计1167例患者,发现与其他疗法相比,灸法能显著提高肿瘤患者放化疗后恶心呕吐的治疗有效率,差异有统计学意义[OR=3.71,95%CI(2.64,5.22),P<0.05]。腧穴使用频次共计48次,包括足三里、内关、中脘、神阙、关元、气海穴等13个穴位。结论灸法防治肿瘤放化疗后恶心呕吐能提高临床疗效,改善患者的生活质量。循证取穴多集中于脾经、任脉等。展开更多
High hydrostatic pressure（HHP） processing is applied to a Konjac glucomannan（KGM）-casein（CS） mixture to explore the changes in the mixture＇s properties and microstructures.The mixture＇s viscosity increases by ...High hydrostatic pressure（HHP） processing is applied to a Konjac glucomannan（KGM）-casein（CS） mixture to explore the changes in the mixture＇s properties and microstructures.The mixture＇s viscosity increases by -18.1% at low HHP（200 MPa） and decreases by about 5.3-31.7% at high HHP（600 MPa）.Scanning electron microscopy analysis shows that low HHP induces a denser and more compact structure,and high HHP leads to a porous and reticular structure.X-ray diffraction shows that the mixture is amorphous without dramatic changes; only some small crystalline peaks appear under excessive pressure.Fourier transform infrared analysis indicates that the non-covalent interactions（hydrogen bonds,etc.） are probably the most important factors for the modification of mixture properties.Bonding enhances under low pressure,and weakens with increasing pressure and time.展开更多
基金Supported by China Postdoctoral Science Foundation(No.2014M551502)National Natural Science Foundation of China(No.31301599)
文摘High hydrostatic pressure（HHP） processing is applied to a Konjac glucomannan（KGM）-casein（CS） mixture to explore the changes in the mixture＇s properties and microstructures.The mixture＇s viscosity increases by -18.1% at low HHP（200 MPa） and decreases by about 5.3-31.7% at high HHP（600 MPa）.Scanning electron microscopy analysis shows that low HHP induces a denser and more compact structure,and high HHP leads to a porous and reticular structure.X-ray diffraction shows that the mixture is amorphous without dramatic changes; only some small crystalline peaks appear under excessive pressure.Fourier transform infrared analysis indicates that the non-covalent interactions（hydrogen bonds,etc.） are probably the most important factors for the modification of mixture properties.Bonding enhances under low pressure,and weakens with increasing pressure and time.
