Vis/NIR spectroscopy,in combination with partial least square(PLS)analysis and a back-propagation neural network,is investigated to identify endothelium corneum gigeriae galli(ECGG).The spectral features of ECGGs and ...Vis/NIR spectroscopy,in combination with partial least square(PLS)analysis and a back-propagation neural network,is investigated to identify endothelium corneum gigeriae galli(ECGG).The spectral features of ECGGs and their counterfeits are reasonably differentiated in vis/NIR region,which provides enough qualitative information to establish the relationship between the spectra and samples for identification.After pretreatment of the spectral data,cross validation is implemented for extracting the best number of principal components.Then the calibration and validation set are performed well.The PLS and back propagation neural network(BPNN)model gives the BPNN to be 0.9941 and the root mean square residual(RMSR)to be 0.0775 for the calibration set,and the multiple correlation coefficient(MCC)to 0.9874 and the RMSE to 0.1134 for the validation set.Thus the PLS and BPNN model is reliable and practicable.Through testing,a recognition accuracy of 100%is achieved.The present study could offer a new approach for fast and nondestructive discrimination of ECGG and its counterfeit.展开更多
Optical coherence tomography(OCT) is used to investigate the microstructure changes of human fingernail induced by hydration.Images of nail plate are obtained to display the morphology of fingernail and to disclose th...Optical coherence tomography(OCT) is used to investigate the microstructure changes of human fingernail induced by hydration.Images of nail plate are obtained to display the morphology of fingernail and to disclose the keratinization of basal cells of nail plate.Combined with digital vernier caliper,this imaging technology is used to evaluate thicknesses and changes of nail in vitro after immersion with time.OCT images of nails show that the dorsal and ventral layers of nails have similar thicknesses which are much thinner than intermediate layer.The total thickness of fingernail exponentially increases with immersion time,and the saturating phenomenon appears at about 12 min.Three layers show different contributions to the total increase of the thickness of 17.4%.Microstructure changes in vivo are similar to the results in vitro.The changes of optical path length also could be evaluated by this method.OCT is capable of reflecting precise microstructure changes,and it has the potential to provide physician with a modern and objective diagnostic standard for nail inspection(NI) and to monitor disorders in Chinese traditional medicine(CTM) clinical practice and research.展开更多
基金Supported by the National Natural Science Foundation of China under Grant No 60878063the Program from Traditional Chinese Medicine Bureau of Guangdong Province(2008233).
文摘Vis/NIR spectroscopy,in combination with partial least square(PLS)analysis and a back-propagation neural network,is investigated to identify endothelium corneum gigeriae galli(ECGG).The spectral features of ECGGs and their counterfeits are reasonably differentiated in vis/NIR region,which provides enough qualitative information to establish the relationship between the spectra and samples for identification.After pretreatment of the spectral data,cross validation is implemented for extracting the best number of principal components.Then the calibration and validation set are performed well.The PLS and back propagation neural network(BPNN)model gives the BPNN to be 0.9941 and the root mean square residual(RMSR)to be 0.0775 for the calibration set,and the multiple correlation coefficient(MCC)to 0.9874 and the RMSE to 0.1134 for the validation set.Thus the PLS and BPNN model is reliable and practicable.Through testing,a recognition accuracy of 100%is achieved.The present study could offer a new approach for fast and nondestructive discrimination of ECGG and its counterfeit.
基金supported by the National Natural Science Foundation of China(60411130595)the Program from Traditional Chinese Medicine Bureau of Guangdong Province(2008233)
文摘Optical coherence tomography(OCT) is used to investigate the microstructure changes of human fingernail induced by hydration.Images of nail plate are obtained to display the morphology of fingernail and to disclose the keratinization of basal cells of nail plate.Combined with digital vernier caliper,this imaging technology is used to evaluate thicknesses and changes of nail in vitro after immersion with time.OCT images of nails show that the dorsal and ventral layers of nails have similar thicknesses which are much thinner than intermediate layer.The total thickness of fingernail exponentially increases with immersion time,and the saturating phenomenon appears at about 12 min.Three layers show different contributions to the total increase of the thickness of 17.4%.Microstructure changes in vivo are similar to the results in vitro.The changes of optical path length also could be evaluated by this method.OCT is capable of reflecting precise microstructure changes,and it has the potential to provide physician with a modern and objective diagnostic standard for nail inspection(NI) and to monitor disorders in Chinese traditional medicine(CTM) clinical practice and research.
