Composite hernia meshes designed in this paper consist of polypropylene( PP) knitted meshes and polycaprolactone( PCL)nanofiber membranes,which are produced by electro-spinning the solution composed of PCL as a solute...Composite hernia meshes designed in this paper consist of polypropylene( PP) knitted meshes and polycaprolactone( PCL)nanofiber membranes,which are produced by electro-spinning the solution composed of PCL as a solute and the mixture of dimethylformamide( DMF) and dichloromethane( DCM) as a solvent. The morphology and diameter of nanofibers in the membrane are well performed when the 15% PCL solution is electrospun under the condition of 18 k V,15 cm,0. 7 m L/h. The poresize of the membranes is less than 10 μm, where such kinds of arrangement are extremely compact to prevent the cells from growing in. The mechanical properties of the membrane with better arrangement state can reach 68. 8 c N/mm^2. The cytotoxicity test of the composite mesh demonstrates the nontoxicity of the materials.However,the bonding fastness between the membrane and the PP mesh is extremely unsubstantial. The better ways to bond PP mesh with PCL membranes should be discussed in the future.展开更多
Polypropylene( PP) is a kind of stable material with excellent mechanical properties. Meshes made of PP have lots of obvious advantages. In this paper,5 PP hernia meshes with different warp-knitting structures which c...Polypropylene( PP) is a kind of stable material with excellent mechanical properties. Meshes made of PP have lots of obvious advantages. In this paper,5 PP hernia meshes with different warp-knitting structures which can be sorted into one light-weight hernia mesh,two standard-weight hernia meshes and two heavyweight hernia meshes were chosen to have a serious of mechanical test,including weight density,thickness,pore size,porosity,tensile strength,bursting strength,stitch tear strength,tear strength and bending rigidity. The respective relationship between mechanical performance and weight density were analyzed. The results revealed that heavy-weight hernia meshes had the biggest thickness( 0. 834 mm),the smallest pore size( 462 μm) and the smallest porosity( 58. 40%). The mechanical performance demonstrated that the tensile strength increased more than 800 N,the stitch tear strength increased more than 40 N,the bursting strength increased more than750 N and the tear strength increased more than 40 N by enlarging the weight density by 100-150 g/m^2. However, heavy-weight hernia meshes had problems of high bending rigidity,unevenness and anisotropy. Standard-weight hernia meshes with 70-140 g/m^2 not only met the demand of the mechanical properties,but also had good flexibility and structure parameters,which could be considered as an ideal hernia mesh.展开更多
基金Biomedical Textile Materials Science and Technology(111 Project),China(No.B07024)
文摘Composite hernia meshes designed in this paper consist of polypropylene( PP) knitted meshes and polycaprolactone( PCL)nanofiber membranes,which are produced by electro-spinning the solution composed of PCL as a solute and the mixture of dimethylformamide( DMF) and dichloromethane( DCM) as a solvent. The morphology and diameter of nanofibers in the membrane are well performed when the 15% PCL solution is electrospun under the condition of 18 k V,15 cm,0. 7 m L/h. The poresize of the membranes is less than 10 μm, where such kinds of arrangement are extremely compact to prevent the cells from growing in. The mechanical properties of the membrane with better arrangement state can reach 68. 8 c N/mm^2. The cytotoxicity test of the composite mesh demonstrates the nontoxicity of the materials.However,the bonding fastness between the membrane and the PP mesh is extremely unsubstantial. The better ways to bond PP mesh with PCL membranes should be discussed in the future.
基金Biomedical Textile Materials Science and Technology,China(111 project)(No.B07024)
文摘Polypropylene( PP) is a kind of stable material with excellent mechanical properties. Meshes made of PP have lots of obvious advantages. In this paper,5 PP hernia meshes with different warp-knitting structures which can be sorted into one light-weight hernia mesh,two standard-weight hernia meshes and two heavyweight hernia meshes were chosen to have a serious of mechanical test,including weight density,thickness,pore size,porosity,tensile strength,bursting strength,stitch tear strength,tear strength and bending rigidity. The respective relationship between mechanical performance and weight density were analyzed. The results revealed that heavy-weight hernia meshes had the biggest thickness( 0. 834 mm),the smallest pore size( 462 μm) and the smallest porosity( 58. 40%). The mechanical performance demonstrated that the tensile strength increased more than 800 N,the stitch tear strength increased more than 40 N,the bursting strength increased more than750 N and the tear strength increased more than 40 N by enlarging the weight density by 100-150 g/m^2. However, heavy-weight hernia meshes had problems of high bending rigidity,unevenness and anisotropy. Standard-weight hernia meshes with 70-140 g/m^2 not only met the demand of the mechanical properties,but also had good flexibility and structure parameters,which could be considered as an ideal hernia mesh.
