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保元大黄汤治疗慢性肾功能衰竭的临床研究 被引量:22
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作者 沈壮雷 李乃英 +4 位作者 葛小平 陈雪帆 赵文国 宋如梅 沈咏慧 《中国中西医结合杂志》 CAS CSCD 北大核心 1994年第5期268-270,共3页
用保元大黄汤(治疗组)治疗慢性肾功能衰竭36例,与包醛氧化淀粉为主的西药综合治疗(对照组)20例比较,两组血BUN、Cr均有降低。但治疗组Hb明显提高,疲劳乏力、腰膝酸软、纳差、性功能障碍和精神抑郁症状显著改善(P<... 用保元大黄汤(治疗组)治疗慢性肾功能衰竭36例,与包醛氧化淀粉为主的西药综合治疗(对照组)20例比较,两组血BUN、Cr均有降低。但治疗组Hb明显提高,疲劳乏力、腰膝酸软、纳差、性功能障碍和精神抑郁症状显著改善(P<0.01),雌二醇、孕酮、睾酮、肌酸磷酸激酶(CPK)比治疗前有明显调整(P<0.01)。对照组症状改善不明显,血红蛋白、性激素水平和CPK治疗前后变化不大。认为保元大黄汤能改善慢性肾功能衰竭患者的生活质量和生活能力,其作用机理与纠正贫血、调整膜功能有关。 展开更多
关键词 肾功能衰竭 保元大黄汤 性激素
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Clinical Study of Chronic Renal Failure Treated with Baoyuan Dahuang Decoction (保元大黄汤)
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作者 沈壮雷 李乃英 +4 位作者 葛小平 陈雪帆 赵文国 宋如梅 沈泳慧 《Chinese Journal of Integrative Medicine》 SCIE CAS 1995年第3期189-193,共5页
Chronic renal failure patients (as test group) under treatment by Baoyuan Dahuang De-coction, other 20 cases (as control group) by western medicine, mainly coated aldehyde oxystain, hadcommonly blood urea nitrogen and... Chronic renal failure patients (as test group) under treatment by Baoyuan Dahuang De-coction, other 20 cases (as control group) by western medicine, mainly coated aldehyde oxystain, hadcommonly blood urea nitrogen and creatinine decreased. But among the test group, the hemoglobin in-creased obviously, the symptons of fatigue, lassitude in loin and legs, lack of appetite, sexual disorder,and mental depression improved markedly (P<0. 01) . and estradiol, progesterone, testosterone as wellas creatine phosphokinase were regulated notably compared with before treatment (P<0.01) . Whereasin the control group, the symptoms were not significantly improved, hemoglobin, levels of sex hormonesand creatine phosphokinase differed slightly. It is concluded that Baoyuan Dahuang Decoction possessesefficacy to improve chronic renal failure patients' vitality and ability, the mechanism of which is related toanemia rectification and membrane function. 展开更多
关键词 chronic renal failure creatine phosphokinase Baoyuan Dahuang Decoction sex hor-mone
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