Arteannuin 1 which was shown to be a new sesquiterpenoid containing a peroxide group is an antimalaria active principle isolated from Artemisia annua L. Now we report the synthesis of Arteannuin degradation product, n...Arteannuin 1 which was shown to be a new sesquiterpenoid containing a peroxide group is an antimalaria active principle isolated from Artemisia annua L. Now we report the synthesis of Arteannuin degradation product, norsesquiterpenoid lactone 10 starting from 10R（+）-citronellal 2 by the reaction sequence as shown in Fig. 1. 2 was submitted to cyelization with zinc bromide to afford the 6R, 7S, 10R（—）isopulegol 3. Hydroboration of 3 with B2H5 followed by treatment with展开更多
Brassinolide (BR) is a new potent growth promoting steroid substance which was first isolated from rape pollen by Grove et al. in 1979. Since then a number of BR analogues, such as homobrassinolide 2 and epibrassinoli...Brassinolide (BR) is a new potent growth promoting steroid substance which was first isolated from rape pollen by Grove et al. in 1979. Since then a number of BR analogues, such as homobrassinolide 2 and epibrassinolide 3, have been discovered in plant. Unnatural compounds with similar structure to brassinolide have展开更多
基金This article was reported at the Sino-American Symposium on Chemistry of natural products in October 1980 Shanghai. Zhu Jie participated in the experimental work
文摘Arteannuin 1 which was shown to be a new sesquiterpenoid containing a peroxide group is an antimalaria active principle isolated from Artemisia annua L. Now we report the synthesis of Arteannuin degradation product, norsesquiterpenoid lactone 10 starting from 10R（+）-citronellal 2 by the reaction sequence as shown in Fig. 1. 2 was submitted to cyelization with zinc bromide to afford the 6R, 7S, 10R（—）isopulegol 3. Hydroboration of 3 with B2H5 followed by treatment with
文摘Brassinolide (BR) is a new potent growth promoting steroid substance which was first isolated from rape pollen by Grove et al. in 1979. Since then a number of BR analogues, such as homobrassinolide 2 and epibrassinolide 3, have been discovered in plant. Unnatural compounds with similar structure to brassinolide have
