Non-Hodgkin’s lymphoma cell leukemia (NHLCL),chronic lymphocytic leukemia (CLL) and hairy cell leukemia (HLC) are the diseases very similar to each other. The differential diagnosis is very difficult,especially when ...Non-Hodgkin’s lymphoma cell leukemia (NHLCL),chronic lymphocytic leukemia (CLL) and hairy cell leukemia (HLC) are the diseases very similar to each other. The differential diagnosis is very difficult,especially when there are small lymphoid cells in Periphcral blood and bone marrow under light microscope. We have observed 34 cases with electron microscope. The studies were correlated with clinical manifestation, cytology, pathology and immunologic histochemistry. Ultrastructural features strongly indicated the difference in three various diseases, although all the immunologic markers showed B-cell type.It is concluded that electron microscopic examination is of a definite significance in the diaguosis and successful treatment.展开更多
The present study analyses two cases with acute immature eosinophilic leukemia. The clinical, physical, laboratory and pathologic materials are discussed. There is an abnormal number of immature eosinophilic cells in ...The present study analyses two cases with acute immature eosinophilic leukemia. The clinical, physical, laboratory and pathologic materials are discussed. There is an abnormal number of immature eosinophilic cells in the blood and bone marrow, usually accompanied by anemia and thrombocytopenia. Especially the ultra-structural features include abnormal granules, asynchronous maturation of the nucleus and cytoplasm, dilated endoplasmic reticulum and more conspicuous nucleoli. Differential count was more precise under electron microscope than under light microscope. These findings may be helpful for differential diagnosis and classification.展开更多
文摘Non-Hodgkin’s lymphoma cell leukemia (NHLCL),chronic lymphocytic leukemia (CLL) and hairy cell leukemia (HLC) are the diseases very similar to each other. The differential diagnosis is very difficult,especially when there are small lymphoid cells in Periphcral blood and bone marrow under light microscope. We have observed 34 cases with electron microscope. The studies were correlated with clinical manifestation, cytology, pathology and immunologic histochemistry. Ultrastructural features strongly indicated the difference in three various diseases, although all the immunologic markers showed B-cell type.It is concluded that electron microscopic examination is of a definite significance in the diaguosis and successful treatment.
文摘The present study analyses two cases with acute immature eosinophilic leukemia. The clinical, physical, laboratory and pathologic materials are discussed. There is an abnormal number of immature eosinophilic cells in the blood and bone marrow, usually accompanied by anemia and thrombocytopenia. Especially the ultra-structural features include abnormal granules, asynchronous maturation of the nucleus and cytoplasm, dilated endoplasmic reticulum and more conspicuous nucleoli. Differential count was more precise under electron microscope than under light microscope. These findings may be helpful for differential diagnosis and classification.
