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半夏泻心汤治疗胃食管反流的作用机制和研究进展
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作者 韦彩容 黄夏冰 甘祥深 《中医学》 2024年第8期2010-2016,共7页
胃食管反流病(GERD),作为一种高发的消化系统疾病,其核心症状表现为反酸与烧心感,严重影响患者的生活质量。西医治疗虽以药物为主,但中医通过整体调节的理念,结合药物、饮食、情志及行为等多方面的干预,展现出独特的治疗优势。中医学认... 胃食管反流病(GERD),作为一种高发的消化系统疾病,其核心症状表现为反酸与烧心感,严重影响患者的生活质量。西医治疗虽以药物为主,但中医通过整体调节的理念,结合药物、饮食、情志及行为等多方面的干预,展现出独特的治疗优势。中医学认为,GERD的病机核心在于“胃失和降,胃气上逆”。这一理论深刻揭示了GERD症状产生的内在原因,即胃的通降功能失常,导致胃内容物反流至食管,引发一系列不适症状。半夏泻心汤能够针对病机,有效缓解反酸、烧心等症状,同时调整患者的整体状态,减少疾病的复发。进一步探究半夏泻心汤治疗GERD的作用机制和药理作用,有助于我们更深入地理解其疗效背后的科学原理。同时,现代药理研究也揭示了该方在调节胃肠动力、抑制胃酸分泌、保护胃黏膜等方面的作用机制,为中医药治疗GERD提供了科学依据。本文的探讨旨在为临床医生提供更深层次的研究思路和参考,推动半夏泻心汤在GERD治疗中的广泛应用和深入研究。Gastroesophageal reflux disease (GERD), as a highly prevalent digestive system disease, is characterized by core symptoms such as acid reflux and heartburn, which seriously affects the quality of life of patients. Although Western medicine treatment mainly relies on medication, traditional Chinese medicine demonstrates unique therapeutic advantages through the concept of holistic regulation, combined with interventions in medication, diet, emotions, and behavior. Traditional Chinese Medicine believes that the core pathogenesis of GERD lies in the “loss of balance and descent of the stomach, and the reversal of stomach qi”. This theory profoundly reveals the underlying cause of GERD symptoms, which is the dysfunction of the stomach’s flow and descent function, leading to the reflux of gastric contents into the esophagus and causing a series of discomfort symptoms. Banxia Xiexin Tang can effectively alleviate symptoms such as acid reflux and heartburn by targeting the pathogenesis, while adjusting the overall state of the patient and reducing the recurrence of the disease. Further exploration of the mechanism and pharmacological effects of Banxia Xiexin Tang in treating GERD will help us better understand the scientific principles behind its therapeutic efficacy. Meanwhile, modern pharmacological research has also revealed the mechanism of action of this formula in regulating gastrointestinal motility, inhibiting gastric acid secretion, and protecting gastric mucosa, providing scientific basis for the treatment of GERD with traditional Chinese medicine. The purpose of this article is to provide clinical doctors with deeper research ideas and references, and to promote the widespread application and in-depth research of Banxia Xiexin Tang in the treatment of GERD. 展开更多
关键词 半夏泻心汤 胃食管反流 中医 药理作用 综述
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基于活血化瘀法中医治疗肝硬化的临床应用进展
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作者 甘祥深 黄古叶 +2 位作者 韦彩容 彭乐 徐莉虹 《中医学》 2024年第9期2129-2135,共7页
运用中医药治疗肝硬化具有多环节和多靶点的优势,临床疗效可观。活血化瘀法作为中医经典治法之一,通过促进血液循环、消散瘀血积聚,有效改善肝脏微循环障碍,减轻肝脏纤维化程度,展现出独特的治疗优势。本文对活血化瘀法运用依据、中医... 运用中医药治疗肝硬化具有多环节和多靶点的优势,临床疗效可观。活血化瘀法作为中医经典治法之一,通过促进血液循环、消散瘀血积聚,有效改善肝脏微循环障碍,减轻肝脏纤维化程度,展现出独特的治疗优势。本文对活血化瘀法运用依据、中医内治、外治诊疗技术治疗肝硬化的文献和临床资料进行分析、概述,为肝硬化临床诊疗、综合治疗提供补充与参考。The application of traditional Chinese medicine (TCM) in the treatment of liver cirrhosis exhibits advantages of multi-faceted and multi-target mechanisms, leading to remarkable clinical efficacy. As one of the classical therapeutic methods in TCM, the blood-activating and stasis-eliminating method effectively alleviates hepatic microcirculatory disturbances and reduces the degree of liver fibrosis by promoting blood circulation and dissipating blood stasis accumulation, thereby demonstrating unique therapeutic benefits. This paper analyzes and summarizes the literature and clinical data on the application rationale, internal and external therapeutic techniques of TCM for treating liver cirrhosis with the blood-activating and stasis-eliminating method. The aim is to provide supplementary information and references for clinical diagnosis, treatment, and comprehensive management of liver cirrhosis. 展开更多
关键词 活血化瘀法 肝硬化 中医药
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