网式无人机捕捉系统性能分析

网式无人机捕捉系统能够完整捕获目标无人机,在民用无人机反制方面具有应用前景。针对网式无人机捕捉系统进行了理论分析,对射程和捕捉网张开时间这两个关键性能进行了分析,建立了相应的数学模型,得到了二者的显示表达式。为网式无人机捕捉系统的设计和选型提供了参考。

Effects of Pachyman in Combination with Vinorelbine and Cisplatin on Tumor Growth and the Expression of EGFR and K-ras in Mice with Lung Cancer

Objective To examine the effects of pachyman in combination with vinorelbine and cisplatin on tumor growth and the expression of epidermal growth factor receptor(EGFR)and K-ras in a mouse model of lung cancer induced using the human lung cancer cell line A549,and to investigate the molecular mechanisms underlying the antitumor effects of pachyman.Methods We recorded the size of the tumor xenografts in mice after treatment with pachyman monotherapy or pachymanin combination with vinorelbine and cisplatin.We performed immunohistochemical analysis to determine the levels of expression and distribution of EGFR and K-ras in lung cancer tissues.Real-time fluorescence quantitative PCR was used to determine the relative mRNA expression levels of EGFR and K-ras in lung cancer tissues.Results Vinorelbine and cisplatin significantly decreased the rate of growth of A549 xenografts,and pachyman increased the efficacy of vinorelbine and cisplatin.EGFR and K-ras were widely expressed in A549 xenografts.Vinorelbine and cisplatin could significantly decrease the expression,distribution and mRNA expression levels of EGFR and K-ras in tumor tissues.Pachyman monotherapy significantly decreased the distribution and the mRNA expression levels of EGFR in lung cancer tissues.In addition,pachyman in combination with vinorelbine and cisplatin markedly decreased the distribution and expression levels of EGFR in lung cancer tissues.However,pachyman monotherapy or combination therapy did not significantly decrease the mRNA expression levels of K-ras.Conclusion Thus,pachyman in combination with vinorelbine can significantly inhibit the growth of A549 xenografts,and pachyman can regulate the expression of the EGFR gene to increase the efficacy of vinorelbine and cisplatin in lung cancer and decrease the side effects associated with chemotherapy.

吹糖人儿

我也好奇地揪住了一个糖尖儿,抻出了小猪的尾巴。——题记走在北京的胡同里,总能远远地听见卖糖人儿的吆喝声。“卖糖人儿嘞——各种生肖都有嘞——”悠长的吆喝声把我的思绪拉回到昔日的岁月中,那个与糖人儿结缘的冬天。北京的冬天很冷,我穿着厚厚的棉衣,和奶奶走在南锣鼓巷的青石路上。巷子里很热闹,有卖粘着糖溃的红薯的,也有卖兔儿爷模样的泥人儿的,而我的目光却被那卖糖人儿的给吸引去了。